Simple molecule GTP
GTP@T_cell
Identifiers
CHEBI:15996 KEGGCOMPOUND:C00044 CAS:86-01-1
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ INHIBITING_CHECKPOINTS
Adaptive Immune Response
/ TCR_SIGNALING
GTP@Mitochondrial Matrix
Identifiers
CHEBI:15996 KEGGCOMPOUND:C00044 CAS:86-01-1
GTP@INNATE_IMMUNE_CELL_Cytosol
Identifiers
CHEBI:15996 KEGGCOMPOUND:C00044 CAS:86-01-1
References
DENDRITIC_CELL
GTP@Cytoplasm
References
s_wnc1_re62( Survival
):
Cthrc1 enhances formation of Wnt-Fzl-Ror2 complex
PMID:12839624
PMID:18606138
Syndecan-4 binds to Fzl, Dvl and is required for PCP MODULE.
PMID:16604063
PMID:21397842
Vangl-2 forms complex upon binding with Wnt-5
PMID:21316585
ROR2 is associated with Wnt, Fzl and CK1_epsilon
PMID:20215527
PPR binds to Fzl in both canonical and non-canonical MODULE
PMID:20093472
PMID:21380625
PMID:20579883
GTP@Vaceolae
References
s_wca1_re25:( Survival
) PMID:21606194 PMID:19705439
Modifications:
In compartment: Cytoplasm
- GTP@Cytoplasm
In compartment: Cytosol
- GTP@Cytosol
In compartment: INNATE_IMMUNE_CELL_Cytosol
- GTP@INNATE_IMMUNE_CELL_Cytosol
In compartment: Mitochondrial Matrix
- GTP@Mitochondrial Matrix
In compartment: T_cell
- GTP@T_cell
In compartment: Vaceolae
- GTP@Vaceolae
Participates in complexes:
In compartment: Cytoplasm
- GTP:RAC1@Cytoplasm
- GTP:G_alpha_*@Cytoplasm
- GTP:G_alpha_o*@Cytoplasm
- GTP:G_alpha__sub_s_endsub_*@Cytoplasm
- GTP:PLC-_beta_*:RAC1@Cytoplasm
- GTP:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
- GTP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6|S1544_pho|T1548_pho@Cytoplasm
- FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
- GTP:G_alpha__sub_13q_endsub_*:G_beta_*:G_gamma_*:PAR1_sub_TRUNC_endsub_*:_beta_-Arrestin*@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
- CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LRP5_6*:WNT*:p120*@Cytoplasm
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
- CK1_epsilon_*:CTHRC1:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:PAR6*:PRICKLE1|pho:PRR*:RACK1*:ROR2:SYN4*:VANGL*:WNT*@Cytoplasm
In compartment: Cytosol
- GTP:RAC1@Cytosol
- GTP:RAF1@Cytosol
- GTP:RAS*@Cytosol
- GNAI1:GTP@Cytosol
- GNAI2:GTP@Cytosol
In compartment: Golgi apparatus
- ARF1:GGA1:GTP@Golgi apparatus
- ARF1:GTP:PTP4A3|pre@Golgi apparatus
In compartment: INNATE_IMMUNE_CELL_Cytosol
- ARF6:GTP@INNATE_IMMUNE_CELL_Cytosol
- GTP:HRAS@INNATE_IMMUNE_CELL_Cytosol
- GTP:RHOB@INNATE_IMMUNE_CELL_Cytosol
- ARL14:GTP@INNATE_IMMUNE_CELL_Cytosol
- GTP:RAC1_2*@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RHEB)|active@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RHOA)|active@INNATE_IMMUNE_CELL_Cytosol
- (CDC42:GTP)|active@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RAP1A)|active@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RAC1_2*)|active@INNATE_IMMUNE_CELL_Cytosol
- ARL14:ARL14EP:GTP:MYO1E@INNATE_IMMUNE_CELL_Cytosol
- CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@INNATE_IMMUNE_CELL_Cytosol
In compartment: Lysosome
- GTP:RHEB@Lysosome
- GDP:GTP:Rag A/B*:Rag C/D*@Lysosome
- GDP:GTP:MLST8:MTOR:RPTOR:Rag A/B*:Rag C/D*@Lysosome
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
- CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
In compartment: Recyclying endosome
- ARF1:GTP:PTP4A3|pre@Recyclying endosome
In compartment: T_cell
- GNAS:GTP@T_cell
- CDC42:GTP@T_cell
- (GTP:HRAS)|active@T_cell
- (GTP:RHEB)|active@T_cell
- (GTP:RAC1_2*)|active@T_cell
- Adenylil_cyclase*:GNAS:GTP@T_cell
In compartment: Vaceolae
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
Participates in reactions:
As Reactant or Product:- ADORA2A:GDP:GNAS:GNB*:GNG*@T_cell
+ GTP@T_cell
→
ADORA2A:GNB*:GNG*@T_cell
+ GDP@T_cell
+ GNAS:GTP@T_cell
- (GTP:RHEB)|active@T_cell
+ GDP@T_cell
→
GDP:RHEB@T_cell
+ GTP@T_cell
- GDP:RAC1_2*@T_cell
+ GTP@T_cell
→
(GTP:RAC1_2*)|active@T_cell
+ GDP@T_cell
- GDP:HRAS@T_cell
+ GTP@T_cell
→
(GTP:HRAS)|active@T_cell
+ GDP@T_cell
- CDC42:GDP@T_cell
+ GTP@T_cell
→
CDC42:GTP@T_cell
+ GDP@T_cell
- GNAS:GTP@T_cell
+ Adenylil_cyclase*@T_cell
→
Adenylil_cyclase*:GNAS:GTP@T_cell
- GDP:RAS*@Cytosol
→
GTP:RAS*@Cytosol
- GDP:RAF1@Cytosol
→
GTP:RAF1@Cytosol
- GDP:GNAI1:GNB1-5:GNG1-5@Cytosol
→
GNAI1:GTP@Cytosol
+ GNB1-5:GNG1-5@Cytosol
- GDP:GNAI2:GNB1-5:GNG1-5@Cytosol
→
GNAI2:GTP@Cytosol
+ GNB1-5:GNG1-5@Cytosol
- GDP:RAS*@Cytosol
→
GTP:RAS*@Cytosol
- GNAI1:GTP@Cytosol
+ GDP:RAC1@Cytosol
→
GTP:RAC1@Cytosol
+ GDP:GNAI1@Cytosol
- GNAI2:GTP@Cytosol
+ GDP:RAC1@Cytosol
→
GTP:RAC1@Cytosol
+ GDP:GNAI2@Cytosol
- GTP:RAF1@Cytosol
→
MAPK pathway activation@Cytosol
- ca_s810 + GTP@Cytosol
→
ca_s813 + GDP@Cytosol
- ca_s1703 + GTP@Cytosol
→
ca_s1700 + GDP@Cytosol
- ca_s94 + GTP@Cytosol
→
ca_s97 + GDP@Cytosol
- GDP:RAS*@Cytosol
+ GTP@Cytosol
→
GTP:RAS*@Cytosol
+ GDP@Cytosol
- RAC1@Cytosol
→
GTP:RAC1@Cytosol
- GDP:RAC1@Cytosol
→
GTP:RAC1@Cytosol
- GTP:RAC1@Cytosol
→
GDP:RAC1@Cytosol
- GTP:RAC1@Cytosol
→
ARHGEF14*@Cytosol
- GTP:RAC1@Cytosol
→
NCKAP1@Cytosol
- GTP:RAC1@Cytosol
→
CYFIP2@Cytosol
- GTP:RAC1@Cytosol
+ NCK1@Cytosol
→
em_emtc_emtc_s3001
- GTP:RAC1@Cytosol
→
Membrane spreading@Cytosol
- GTP:RAC1@Cytosol
+ IQGAP1@Cytosol
→
em_s2321
- GDP:RAC1_2*@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
(GTP:RAC1_2*)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- GDP:RHOA@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
(GTP:RHOA)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RHEB)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
→
GDP:RHEB@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
- GDP:RAP1A@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
(GTP:RAP1A)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RAP1A)|active@INNATE_IMMUNE_CELL_Cytosol
→
Conjugate_formation@INNATE_IMMUNE_CELL_Membrane
- CDC42:GDP@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
(CDC42:GTP)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- ARL14:GDP@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
ARL14:GTP@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- GDP:HRAS@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
GTP:HRAS@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- ARF6:GDP@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
ARF6:GTP@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- ARL14:GTP@INNATE_IMMUNE_CELL_Cytosol
+ ARL14EP@INNATE_IMMUNE_CELL_Cytosol
+ MYO1E@INNATE_IMMUNE_CELL_Cytosol
→
ARL14:ARL14EP:GTP:MYO1E@INNATE_IMMUNE_CELL_Cytosol
- GDP:RHOB@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
→
GTP:RHOB@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
- GTP:RAC1_2*@INNATE_IMMUNE_CELL_Cytosol
+ NCF2@INNATE_IMMUNE_CELL_Cytosol
+ NCF4@INNATE_IMMUNE_CELL_Cytosol
+ CYBA@INNATE_IMMUNE_CELL_Cytosol
+ NCF1@INNATE_IMMUNE_CELL_Cytosol
+ CYBB@INNATE_IMMUNE_CELL_Cytosol
+ FAD@INNATE_IMMUNE_CELL_Cytosol
+ heme@INNATE_IMMUNE_CELL_Cytosol
→
CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@INNATE_IMMUNE_CELL_Cytosol
- (GTP:RAC1_2*)|active@INNATE_IMMUNE_CELL_Cytosol
→
EXOCYTOSIS_AND_PHAGOCYTOSIS@INNATE_IMMUNE_CELL_Membrane
- GDP:RHEB@Lysosome
→
GTP:RHEB@Lysosome
- GTP:RHEB@Lysosome
→
GDP:RHEB@Lysosome
- Rag A/B*:Rag C/D*@Cytosol
+ mo_s16 →
GDP:GTP:MLST8:MTOR:RPTOR:Rag A/B*:Rag C/D*@Lysosome
- GDP:GTP:MLST8:MTOR:RPTOR:Rag A/B*:Rag C/D*@Lysosome
→
GDP:GTP:Rag A/B*:Rag C/D*@Lysosome
+ MLST8:MTOR:RPTOR@Lysosome
- mo_s204 + GGA1@Cytosol
→
ARF1:GGA1:GTP@Golgi apparatus
- ARF1:GTP:PTP4A3|pre@Golgi apparatus
→
ARF1:GTP:PTP4A3|pre@Recyclying endosome
- ARF1:GTP:PTP4A3|pre@Recyclying endosome
→
ITGA5 & TFRC recycling@Cytosol
- GTP:RAC1@Cytosol
→
GDP:RAC1@Cytosol
- GDP:GTP:MLST8:MTOR:RPTOR:Rag A/B*:Rag C/D*@Lysosome
→
Cell cycle / survival / proliferation@Cytosol
- PTP4A3|pre@Golgi apparatus
+ mo_s204 →
ARF1:GTP:PTP4A3|pre@Golgi apparatus
- GTP@Cytosol
+ ATP@Cytosol
+ UTP@Cytosol
+ CTP@Cytosol
→
rRNA@Cytosol
- GTP@Cytosol
→
cGMP@Cytosol
+ Pyrophosphate@Cytosol
- rc_s5973 + GTP@Cytosol
→
rc_s5974 + GDP@Cytosol
- purine ribonucleoside 5'-triphosphate@Cytosol
→
GTP@Cytosol
+ ATP@Cytosol
- EIF2S1:EIF2S2:EIF2S3:Met-tRNA*@Cytosol
+ GTP@Cytosol
→
BAX:EIF2S2:EIF2S3:Met-tRNA*@Cytosol
+ GDP@Cytosol
- BAX:EIF2S2:EIF2S3:Met-tRNA*@Cytosol
+ GDP@Cytosol
→
EIF2S1:EIF2S2:EIF2S3:Met-tRNA*@Cytosol
+ GTP@Cytosol
- succinyl-CoA@Mitochondrial Matrix
+ GDP@Mitochondrial Matrix
→
succinate@Mitochondrial Matrix
+ coenzyme A@Mitochondrial Matrix
+ GTP@Mitochondrial Matrix
- su_shh1_s635 + G_alpha__sub_i_endsub_*:G_beta__sub_i_endsub_*:G_gamma__sub_i_endsub_*@Cytosol
+ GTP@Cytosol
→
G_alpha__sub_i_endsub_*:G_beta__sub_i_endsub_*:G_gamma__sub_i_endsub_*:HH Ligand@Cytosol
+ GDP@Cytosol
- GDP:RAC1@Cytosol
+ GTP@Cytosol
→
GTP:RAC1@Cytosol
+ GDP@Cytosol
- GTP:RAC1@Cytosol
→
EMT@Cytosol
- G_alpha__sub_i_endsub_*:HH Ligand@Cytosol
+ GTP@Cytosol
→
G_alpha__sub_i_endsub_*:Ligand@Cytosol
+ GDP@Cytosol
- WNT*@default
+ CK1_epsilon_*:E-Cadherin*:LRP5_6*:p120*@Vaceolae
+ FZD*:GDP:G_alpha_o*:G_beta_*:G_gamma_*@Cytoplasm
+ GTP@Vaceolae
+ PRR*@Cytoplasm
→
CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ GDP@Vaceolae
- DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ AMER1*:CK1_gamma_*:PtdIns(4,5)-P2@Cytoplasm
→
AMER1*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:_beta_-Arrestin2*:p120*@Vaceolae
+ GTP:G_alpha_o*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
- GTP:G_alpha_o*@Cytoplasm
+ AXIN*:CK1_alpha_*:GSK3*@Cytoplasm
+ _beta_-Arrestin2*@Cytoplasm
→
AXIN*:CK1_alpha_*:GSK3*:G_alpha_o*:_beta_-Arrestin2*@Cytoplasm
- GTP:G_alpha_o*@Cytoplasm
→
GDP:G_alpha_o*@Cytoplasm
+ Pi@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→
LRP5_6*@Cytoplasm
+ E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
- LRP5_6*@Cytoplasm
→
E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→
WNT canonical pathway@Cytoplasm
- CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→
WNT canonical pathway@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
+ CRIPTO-1*:LRP5_6*@Cytoplasm
→
CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
- GTP:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
+ DVL*|pho|S142_emp|S139_emp@Cytoplasm
→
DVL*|pho:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
- LGR5:RSPO1-4*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LRP5_6*:WNT*:p120*@Cytoplasm
→
CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
→
WNT canonical pathway@Cytoplasm
- GTP:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
+ PLC-_beta_*@Cytoplasm
→
G_alpha__sub_13q_endsub_*:PLC-_beta_*:_beta_-Arrestin*@Cytoplasm
- PTH@default
+ G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6@Cytoplasm
+ GTP@Cytoplasm
→
G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6:PTH@Cytoplasm
+ GDP@Cytoplasm
- G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6:PTH@Cytoplasm
→
GTP:G_alpha__sub_s_endsub_*@Cytoplasm
+ LRP6@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
+ PTH@default
- LRP6|S1544_pho|T1548_pho@Cytoplasm
+ GDP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*@Cytoplasm
+ GTP@Cytoplasm
→
GTP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6|S1544_pho|T1548_pho@Cytoplasm
+ GDP@Cytoplasm
+ LRP6|S1544_pho|T1548_pho@Cytoplasm
- GTP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*:LRP6|S1544_pho|T1548_pho@Cytoplasm
→
GTP:G_alpha__sub_s_endsub_*@Cytoplasm
+ GDP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*@Cytoplasm
- WNT*@default
+ FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ GTP@Cytoplasm
→
FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
+ GDP@Cytoplasm
- FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
→
G_beta_*:G_gamma_*@Cytoplasm
+ GTP:G_alpha_*@Cytoplasm
- GTP:G_alpha_*@Cytoplasm
→
GDP:G_alpha_*@Cytoplasm
+ Pi@Cytoplasm
- GTP:G_alpha_*@Cytoplasm
→
GTP:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
- GTP:G_alpha__sub_s_endsub_*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
→
GDP:G_alpha__sub_s_endsub_*:G_beta_*:G_gamma_*@Cytoplasm
- GTP:RAC1@Cytoplasm
+ PLC-_beta_*@Cytoplasm
→
GTP:PLC-_beta_*:RAC1@Cytoplasm
- ROR2@Cytoplasm
+ FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ WNT*@default
+ GTP@Cytoplasm
+ CK1_epsilon_*@Cytoplasm
+ CTHRC1@Cytoplasm
+ SYN4*@Cytoplasm
+ PAR6*:PRICKLE1|pho:RACK1*:VANGL*@Cytoplasm
+ PRR*@Cytoplasm
→
CK1_epsilon_*:CTHRC1:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:PAR6*:PRICKLE1|pho:PRR*:RACK1*:ROR2:SYN4*:VANGL*:WNT*@Cytoplasm
+ GDP@Cytoplasm
- CK1_epsilon_*:CTHRC1:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:PAR6*:PRICKLE1|pho:PRR*:RACK1*:ROR2:SYN4*:VANGL*:WNT*@Cytoplasm
→
GTP:G_alpha_*@Cytoplasm
+ CK1_epsilon_*:CTHRC1:FZD*:PAR6*:PRICKLE1|pho:PRR*:RACK1*:ROR2:SYN4*:VANGL*:WNT*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
- GDP:G_alpha__sub_13q_endsub_*:G_beta_*:G_gamma_*:PAR1_sub_TRUNC_endsub_*@Cytoplasm
+ GTP@Cytoplasm
+ _beta_-Arrestin*@Cytoplasm
→
GTP:G_alpha__sub_13q_endsub_*:G_beta_*:G_gamma_*:PAR1_sub_TRUNC_endsub_*:_beta_-Arrestin*@Cytoplasm
+ GDP@Cytoplasm
- GTP:G_alpha__sub_13q_endsub_*:G_beta_*:G_gamma_*:PAR1_sub_TRUNC_endsub_*:_beta_-Arrestin*@Cytoplasm
→
PAR1_sub_TRUNC_endsub_*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
+ GTP:G_alpha__sub_13q_endsub_*:_beta_-Arrestin*@Cytoplasm
As Catalyser:- Actin cytoskeletal*|hm2@T_cell
→
Actin polymerization@T_cell
- PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@T_cell
→
Centrosome polarization@T_cell
- DEPTOR:MLST8:MTOR:PRAS40*:RPTOR@T_cell
→
(DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@T_cell
- PAK1@T_cell
→
PAK1@T_cell
- MAP3K1@T_cell
→
MAP3K1@T_cell
- RAF1@T_cell
→
RAF1|pho@T_cell
- DAG:PRKCQ@T_cell
→
DAG:PRKCQ@cSMAC
- GRAP:GRAP2:GRB2:LAT|pho:PLCG1@T_cell
→
GRAP:GRAP2:GRB2:LAT|pho:PLCG1|pho@T_cell
- ATP@T_cell
→
cAMP@T_cell
- GDP:RAF1@Cytosol
→
GTP:RAF1@Cytosol
- FAK*@Cytosol
→
FAK*|activated@Cytosol
- RAF*@Cytosol
→
RAF*@Cytosol
- LEF1_TCF3_4*@Nucleus
+ _beta_-Catenin*@Cytosol
→
LEF1_TCF3_4*:_beta_-Catenin*@Nucleus
- PAK*@Cytosol
→
PAK*|pho|active@Cytosol
- MAP3K7_10_11*@Cytosol
→
MAP3K7_10_11*@Cytosol
- PAR6*@Cytosol
→
PAR6*@Cytosol
- ARFIP2@Cytosol
→
ARFIP2@Cytosol
- PIP5K1*@Cytosol
→
PIP5K1*@Cytosol
- BAIAP2@Cytosol
→
BAIAP2@Cytosol
- PAK1@Cytosol
+ NISCH@Nucleus
→
NISCH:PAK1@Cytosol
- E-Cadherin*|Y_pho@Cytosol
→
E-Cadherin*|Y_pho@Caveolin vesicle
- E-Cadherin*|Y_pho@Cytosol
→
E-Cadherin*|Y_pho@Macropinosome
- Cadherin*:_alpha_-Catenin*:_beta_-Catenin*:p120*@Cytosol
→
E-Cadherin*@Caveolin vesicle
- Cadherin*:_alpha_-Catenin*:_beta_-Catenin*:p120*@Cytosol
→
E-Cadherin*@Macropinosome
- DEPTOR:MLST8:MTOR:PRAS40*:RPTOR@INNATE_IMMUNE_CELL_Cytosol
→
(DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@INNATE_IMMUNE_CELL_Cytosol
- WASP*@INNATE_IMMUNE_CELL_Cytosol
→
WASP*|pho|active@INNATE_IMMUNE_CELL_Cytosol
- ATP@INNATE_IMMUNE_CELL_Cytosol
→
cGAMP@INNATE_IMMUNE_CELL_Cytosol
- PAK1@INNATE_IMMUNE_CELL_Cytosol
→
PAK1@INNATE_IMMUNE_CELL_Cytosol
- ROCK1@INNATE_IMMUNE_CELL_Cytosol
→
ROCK1@INNATE_IMMUNE_CELL_Cytosol
- O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
→
O_sub_2_endsub__super_-_endsuper_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
- RASSF5@INNATE_IMMUNE_CELL_Cytosol
+ MST1@INNATE_IMMUNE_CELL_Cytosol
→
MST1|pho:RASSF5@INNATE_IMMUNE_CELL_Cytosol
- MHC_class_II*:Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
→
MHC_class_II*:Tumor_antigen_fragment@INNATE_IMMUNE_CELL_Membrane
- RAF1@INNATE_IMMUNE_CELL_Cytosol
→
RAF1|pho@INNATE_IMMUNE_CELL_Cytosol
- PLD*@INNATE_IMMUNE_CELL_Cytosol
→
PLD*@INNATE_IMMUNE_CELL_Cytosol
- PIP5K1A@INNATE_IMMUNE_CELL_Cytosol
→
PIP5K1A@INNATE_IMMUNE_CELL_Cytosol
- O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol
→
O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol
- WASL@INNATE_IMMUNE_CELL_Cytosol
→
WASL|pho|active@INNATE_IMMUNE_CELL_Cytosol
- MLST8:MTOR:RPTOR@Lysosome
→
MLST8:MTOR|S2448_pho:RPTOR@Lysosome
- ITGA5@Cytosol
→
ITGA5@Recyclying endosome
- TFRC@Cytosol
→
TFRC@Recyclying endosome
- DVL*@Cytoplasm
+ CUL3:KLHL*:RBX1@Cytoplasm
→
CUL3:DVL*:KLHL*:RBX1@Cytoplasm
- JBN*:_beta_-Catenin*@Cytoplasm
→
JBN*:_beta_-Catenin*@Cilium
- JBN*:_beta_-Catenin*@Cilium
→
su_wca1_s_wca1_s764
- ATP6V0C_D*@Vaceolae
→
ATP6V0C_D*@Vaceolae
- PI4,5-P2@Cytoplasm
→
DAG@Cytoplasm
+ IP3@Cytoplasm
- Adenylyl_cyclase*@Cytoplasm
→
Adenylyl_cyclase*@Cytoplasm