Protein NCK1
Identifiers
HUGO:NCK1
NCK adaptor protein 1
HUGO:NCK1 HGNC:7664 ENTREZ:4690 UNIPROT:P16333
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ TCR_SIGNALING
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence
/ EMT_REGULATORS
EMT Senescence
/ CYTOSKELETON_POLARITY
References
PMID:24670066
Modifications:
In compartment: Cytosol
- NCK1@Cytosol
In compartment: Extracellular Matrix
- NCK1@Extracellular Matrix
In compartment: T_cell
- NCK1@T_cell
Participates in complexes:
In compartment: Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
Participates in reactions:
As Reactant or Product:- KDR|Y1175_emp|1054_pho:NRP1:VEGFA:VEGFB@Cytosol
+ GRB2@Extracellular Matrix
+ SHP1*@Extracellular Matrix
+ NCK1@Extracellular Matrix
+ SHC1@Extracellular Matrix
+ SHP2*@Extracellular Matrix
→
GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
→
FAK*@Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
→
GRB2:SHC1:SOS*@Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
→
PKC activation@Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
→
p38*@Cytosol
- GRB2:KDR|Y1175_pho|1054_pho:NCK1:NRP1:SHC1:SHP1*:SHP2*:VEGFA:VEGFB@Cytosol
→
PKC activation@Cytosol
- NCK1@Cytosol
+ NCKAP1@Cytosol
→
em_emtc_emtc_s2998
- GTP:RAC1@Cytosol
+ NCK1@Cytosol
→
em_emtc_emtc_s3001
As Catalyser:- PAK1@T_cell
→
PAK1@T_cell
- SYK@Cytosol
→
SYK|pho@Cytosol
- PIK3R1:PIK3R2@Cytosol
→
PIK3R1|pho:PIK3R2@Cytosol
- PLCG1@Cytosol
→
PLCG1|pho@Cytosol
- FAK*@Cytosol
→
FAK*|pho@Cytosol
- FYN@Cytosol
→
FYN|pho@Cytosol