CK1_epsilon

Protein CK1_epsilon_*

Identifiers
casein kinase 1, epsilon
HUGO:CSNK1E HGNC:2453 ENTREZ:1454 UNIPROT:P49674
HUGO:CSNK1E HGNC:2453 ENTREZ:1454 UNIPROT:P49674 GENECARDS:CSNK1E REACTOME:57871 KEGG:1454 ATLASONC:GC_CSNK1E WIKI:CSNK1E

Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / APOPTOSIS
Regulated Cell Death / MOMP_REGULATION
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_CANONICAL
Survival / WNT_NON_CANONICAL

References
PMID:7641885

CK1_epsilon_*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / APOPTOSIS
Regulated Cell Death / MOMP_REGULATION

References
rc_re509( Regulated Cell Death ):
PMID:11583622
BID phosphorylated in Hela, in L929 (murine fibrosarcoma cell line), in other cell lines
mass spectrometry analysis of BID phosphorylated in vitro by Jurkat or Hela extracts
mutagenesis experiments identifies S61 and S64 as the main phosphorylation site
purification of kinase activity in 3 different chromatography fractions
CSNK inhibits Fas-induced apoptosis in Hela D98/AH2 (Fas sensitive Hela)
PMID:12598529
by CSNK2 at T59
PMID:20356928

CK1_epsilon_*@Cytoplasm

References
s_wnc2_re46( Survival ):
Upon Ca2+ activation the NRON-NFAT complex dissociates.
PMID:21709260
s_wnc1_re62( Survival ):
Cthrc1 enhances formation of Wnt-Fzl-Ror2 complex
PMID:12839624
PMID:18606138
Syndecan-4 binds to Fzl, Dvl and is required for PCP MODULE.
PMID:16604063
PMID:21397842
Vangl-2 forms complex upon binding with Wnt-5
PMID:21316585
ROR2 is associated with Wnt, Fzl and CK1_epsilon
PMID:20215527
PPR binds to Fzl in both canonical and non-canonical MODULE
PMID:20093472
PMID:21380625
PMID:20579883

Modifications:
In compartment: Cytoplasm

CK1_epsilon_*@Cytoplasm
CK1_epsilon_*@Cytoplasm

In compartment: Cytosol

CK1_epsilon_*@Cytosol

Participates in complexes:
In compartment: Cytoplasm

In compartment: Endosome

In compartment: Vaceolae

Participates in reactions:
As Reactant or Product:

As Catalyser: