Simple molecule succinate map
succinate@Mitochondrial Matrix

Identifiers
CHEBI:30031 KEGGCOMPOUND:C00042 CAS:56-14-4

References
charge:2-

succinate@Mitochondrial intermembrane space

Identifiers
CHEBI:15741

succinate@Nucleus

Identifiers
CHEBI:15741

References
rc_re397( Regulated Cell Death  map ):
PMID:11641274
PMID:12080085
PMID:12042299
PMID:12215170
PMID:22841746

succinate@Cytosol

References
rc_re387( Regulated Cell Death  map ):
PMID:12351678
identification of PHD2 as a HIF1A prolyl hydroxylase
PMID:15652751
inhibition of HIF1A prolyl hydroxylation by succinate and fumarate
PMID:15721254
in 293 cells, OS9 interacts with HIF1 and PHD and promotes HIF1A prolylhydroxylation and degradation

Modifications:
In compartment: Cytosol
  1. succinate@Cytosol map
In compartment: Mitochondrial Matrix
  1. succinate@Mitochondrial Matrix map
In compartment: Mitochondrial intermembrane space
  1. succinate@Mitochondrial intermembrane space map
In compartment: Nucleus
  1. succinate@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. succinate@Mitochondrial Matrix map → map succinate@Mitochondrial intermembrane space map
    2. succinate@Mitochondrial intermembrane space map → map succinate@Cytosol map
    3. succinate@Mitochondrial Matrix map + ubiquinone@Mitochondrial inner membrane map → map fumarate@Mitochondrial Matrix map + ubiquinol@Mitochondrial inner membrane map
    4. succinyl-CoA@Mitochondrial Matrix map + GDP@Mitochondrial Matrix map → map succinate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map + GTP@Mitochondrial Matrix map
    As Catalyser:
    1. HIF1A@Cytosol map + 2-oxoglutarate:​CUL2:​O_sub_2_endsub_:​RACK1*:​RBX1:​TCEB1:​TCEB2:​VHL@Cytosol map + 2-oxoglutarate:​CUL2:​O_sub_2_endsub_:​RACK1*:​RBX1:​TCEB1:​TCEB2:​VHL@Cytosol map → map HIF1A|​P564_hyd@Cytosol map + succinate@Cytosol map + CO_sub_2_endsub_@Cytosol map
    2. HIF1A:​HIF1B*@Nucleus map + O_sub_2_endsub_@Nucleus map + 2-oxoglutarate@Nucleus map → map rc_s5678 + CO_sub_2_endsub_@Nucleus map + succinate@Nucleus map