Complex CRIPTO-1*:LRP5_6*
Complex composition:
- LRP5_6*
- CRIPTO-1*
CRIPTO-1*:LRP5_6*@Cytoplasm
Identifiers
NAME:CRIPTO-1*:LRP5_6*
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
s_wca2_re70:( Survival
) PMID:23022962
s_wca2_re72( Survival
):
Upon WNT3a CRIPTO-1 binds to LRP5/6 this binding is competing with DKK binding
PMID:23022962
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- CRIPTO-1*:LRP5_6*@Cytoplasm
Participates in reactions:
As Reactant or Product:- LRP5_6*@Cytoplasm
+ CRIPTO-1*@Cytoplasm
→
CRIPTO-1*:LRP5_6*@Cytoplasm
- E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
+ CRIPTO-1*:LRP5_6*@Cytoplasm
→
CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
As Catalyser: