Simple molecule heme
heme@Cytosol
Identifiers
CHEBI:30413
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts
/ METABOLIC
heme@Mitochondrial intermembrane space
Identifiers
CHEBI:30413
References
rc_re1447:( Regulated Cell Death
) reactionType:is.a
heme@Nucleus
Identifiers
CHEBI:30413
References
rc_re1741:( Regulated Cell Death
) PMID:11387216
Modifications:
In compartment: Cytosol
- heme@Cytosol
In compartment: INNATE_IMMUNE_CELL_Cytosol
- heme@INNATE_IMMUNE_CELL_Cytosol
In compartment: Mitochondrial intermembrane space
- heme@Mitochondrial intermembrane space
In compartment: Nucleus
- heme@Nucleus
Participates in complexes:
In compartment: Cytosol
- CYBA:NOX4:POLDIP2:heme@Cytosol
In compartment: INNATE_IMMUNE_CELL_Cytosol
- CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@INNATE_IMMUNE_CELL_Cytosol
In compartment: Nucleus
- BACH1:heme@Nucleus
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
- CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
Participates in reactions:
As Reactant or Product:- CYBA@Cytosol
+ NOX4@Cytosol
+ heme@Cytosol
+ POLDIP2@Cytosol
→
CYBA:NOX4:POLDIP2:heme@Cytosol
- GTP:RAC1_2*@INNATE_IMMUNE_CELL_Cytosol
+ NCF2@INNATE_IMMUNE_CELL_Cytosol
+ NCF4@INNATE_IMMUNE_CELL_Cytosol
+ CYBA@INNATE_IMMUNE_CELL_Cytosol
+ NCF1@INNATE_IMMUNE_CELL_Cytosol
+ CYBB@INNATE_IMMUNE_CELL_Cytosol
+ FAD@INNATE_IMMUNE_CELL_Cytosol
+ heme@INNATE_IMMUNE_CELL_Cytosol
→
CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@INNATE_IMMUNE_CELL_Cytosol
- rc_s4239 + NOXO*@Cytosol
+ NOXA*@Cytosol
+ heme@Cytosol
+ CYBA@Cytosol
+ NOX*@Cytosol
+ FAD@TNFRSF1 Receptor Complex
→
FAD:NOX*:NOXA*:NOXO*@Cytosol
- heme a@Mitochondrial intermembrane space
→
heme@Mitochondrial intermembrane space
- heme o@Mitochondrial intermembrane space
→
heme@Mitochondrial intermembrane space
- heme@Mitochondrial intermembrane space
→
heme@Cytosol
- heme@Cytosol
→
heme@Nucleus
- BACH1@Nucleus
+ heme@Nucleus
→
BACH1:heme@Nucleus
- ALAS1@Cytosol
+ heme@Cytosol
→
rc_s2699
- BACH1:heme@Nucleus
→
rc_s7850
- BACH1@Cytosol
+ heme@Cytosol
→
rc_s7850
As Catalyser:- O_sub_2_endsub_@Cytosol
→
O_sub_2_endsub__super_-_endsuper_@Cytosol
- O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
→
O_sub_2_endsub__super_-_endsuper_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
- O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol
→
O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol