Reaction positive_influence em_emtc_emtc_re767 map

GTP:​RAC1@Cytosol map → ARHGEF14*@Cytosol map

No reaction regulators

References
PMID:14701795
Activated Rac1 activates ARHGEF14 which is a common activator for CDC2 and RHOA
Co-expression of Dbs with activated Rac1 causes enhanced focus forming activity and elevated levels of GTP-bound RhoA in NIH 3T3 cells, indicating that Dbs is activated by the interaction.