Simple molecule FAD map
FAD@Mitochondrial inner membrane

Identifiers
CHEBI:16238 KEGGCOMPOUND:C00016 CAS:146-14-5

FAD@TNFRSF1 Receptor Complex

Identifiers
CHEBI:16238

References
rc_re1364( Regulated Cell Death  map ):
PMID:19641494
RFK in TNF-induced activation of NADPH oxidase
PMID:12440767
review NADPH oxidases

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. FAD@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Mitochondrial inner membrane
  1. FAD@Mitochondrial inner membrane map
In compartment: TNFRSF1 Receptor Complex
  1. FAD@TNFRSF1 Receptor Complex map
Participates in complexes:
In compartment: Cytosol
  1. FAD:​GSR@Cytosol map
  2. FAD:​TXNRD1@Cytosol map
  3. FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map
  4. FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map
  5. ENOS*:​FAD:​FMN:​heme b:​tetrahydrobiopterin@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CYBA:​CYBB:​FAD:​GTP:​NCF1:​NCF2:​NCF4:​RAC1_2*:​heme@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Mitochondrial Matrix
  1. DLD:​DLST:​FAD:​OGDH@Mitochondrial Matrix map
  2. DLAT|​lipoylated:​DLD:​FAD:​PDHA*:​thiamine diphosphate@Mitochondrial Matrix map
  3. DLAT|​lipoylated:​DLD:​FAD:​PDHA*|​pho:​thiamine diphosphate@Mitochondrial Matrix map
In compartment: Mitochondrial inner membrane
  1. FAD:​SDHA@Mitochondrial inner membrane map
  2. AIFM1:​FAD@Mitochondrial inner membrane map
  3. FAD:​SDHA:​SDHB|​[2Fe-2S],[4Fe-4S],[3Fe-4S]:​SDHC:​SDHD:​cardiolipin:​heme b:​phosphatidylethanolamine@Mitochondrial inner membrane map
In compartment: Mitochondrial intermembrane space
  1. FAD:​PPOX@Mitochondrial intermembrane space map
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
  1. CYBA:​CYBB:​FAD:​GTP:​NCF1:​NCF2:​NCF4:​RAC1_2*:​heme@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
Participates in reactions:
As Reactant or Product:
  1. GTP:​RAC1_2*@INNATE_IMMUNE_CELL_Cytosol map + NCF2@INNATE_IMMUNE_CELL_Cytosol map + NCF4@INNATE_IMMUNE_CELL_Cytosol map + CYBA@INNATE_IMMUNE_CELL_Cytosol map + NCF1@INNATE_IMMUNE_CELL_Cytosol map + CYBB@INNATE_IMMUNE_CELL_Cytosol map + FAD@INNATE_IMMUNE_CELL_Cytosol map + heme@INNATE_IMMUNE_CELL_Cytosol map → map CYBA:​CYBB:​FAD:​GTP:​NCF1:​NCF2:​NCF4:​RAC1_2*:​heme@INNATE_IMMUNE_CELL_Cytosol map
  2. TXNRD1@Cytosol map → map FAD:​TXNRD1@Cytosol map
  3. FMN@TNFRSF1 Receptor Complex map + ATP@Cytosol map → map FAD@TNFRSF1 Receptor Complex map
  4. rc_s4239 + NOXO*@Cytosol map + NOXA*@Cytosol map + heme@Cytosol map + CYBA@Cytosol map + NOX*@Cytosol map + FAD@TNFRSF1 Receptor Complex map → map FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map
  5. FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map + rc_s4026 → map FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map
  6. FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map → map ROS Production@Cytosol map
  7. ENOS*@Cytosol map → map ENOS*:​FAD:​FMN:​heme b:​tetrahydrobiopterin@Cytosol map
  8. DLAT|​lipoylated:​DLD:​FAD:​PDHA*|​pho:​thiamine diphosphate@Mitochondrial Matrix map → map DLAT|​lipoylated:​DLD:​FAD:​PDHA*:​thiamine diphosphate@Mitochondrial Matrix map
  9. DLAT|​lipoylated:​DLD:​FAD:​PDHA*:​thiamine diphosphate@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map → map DLAT|​lipoylated:​DLD:​FAD:​PDHA*|​pho:​thiamine diphosphate@Mitochondrial Matrix map + ADP@Mitochondrial Matrix map
  10. SDHA@Mitochondrial inner membrane map + FAD@Mitochondrial inner membrane map → map FAD:​SDHA@Mitochondrial inner membrane map
  11. degraded + FAD:​SDHA@Mitochondrial inner membrane map + SDHB@Mitochondrial inner membrane map + SDHC@Mitochondrial inner membrane map + SDHD@Mitochondrial inner membrane map → map FAD:​SDHA:​SDHB|​[2Fe-2S],[4Fe-4S],[3Fe-4S]:​SDHC:​SDHD:​cardiolipin:​heme b:​phosphatidylethanolamine@Mitochondrial inner membrane map
  12. AIFM1@Mitochondrial inner membrane map + FAD@Mitochondrial inner membrane map → map AIFM1:​FAD@Mitochondrial inner membrane map
As Catalyser:
  1. O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map O_sub_2_endsub__super_-_endsuper_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
  2. O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map → map O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol map
  3. GSSG@Cytosol map + NADPH@Cytosol map → map GSH@Cytosol map + NADP_super_+_endsuper_@Cytosol map
  4. O_sub_2_endsub_@Cytosol map + NADPH@Cytosol map → map O_sub_2_endsub__super_-_endsuper_@Cytosol map + NADP_super_+_endsuper_@Cytosol map
  5. L-arginine@Cytosol map + O_sub_2_endsub_@Cytosol map + NADPH@Cytosol map → map NO@Cytosol map + L-citrulline@Cytosol map + NADP_super_+_endsuper_@Cytosol map
  6. succinate@Mitochondrial Matrix map + ubiquinone@Mitochondrial inner membrane map → map fumarate@Mitochondrial Matrix map + ubiquinol@Mitochondrial inner membrane map
  7. 2-oxoglutarate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map + NAD_super_+_endsuper_@Mitochondrial Matrix map → map succinyl-CoA@Mitochondrial Matrix map + H+@Mitochondrial Matrix map + CO_sub_2_endsub_@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map
  8. pyruvate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map + NAD_super_+_endsuper_@Mitochondrial Matrix map → map acetyl-CoA@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map + CO_sub_2_endsub_@Mitochondrial Matrix map + H+@Mitochondrial Matrix map
  9. degraded + NDUFS8@Mitochondrial inner membrane map + MT-ND5@Mitochondrial inner membrane map + MT-ND4@Mitochondrial inner membrane map + MT-ND4L@Mitochondrial inner membrane map + MT-ND3@Mitochondrial inner membrane map + MT-ND2@Mitochondrial inner membrane map + MT-ND1@Mitochondrial inner membrane map + MT-ND6@Mitochondrial inner membrane map → map FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map
  10. protoporphyrinogen@Mitochondrial intermembrane space map + O_sub_2_endsub_@Mitochondrial intermembrane space map → map protoporphyrin IX@Mitochondrial intermembrane space map
  11. TXN|​-S-S-@Cytosol map + NADPH@Cytosol map → map TXN@Cytosol map + NADP_super_+_endsuper_@Cytosol map