Complex MLST8:MTOR:RPTOR map
Complex composition:

  1. MLST8 map
  2. MTOR map
  3. RPTOR map

MLST8:​MTOR:​RPTOR@Lysosome

Identifiers
NAME:MLST8:MTOR:RPTOR

References
mo_re188:( motility  map ) PMID:26597054
mo_re189:( motility  map ) PMID:26597054 PMID:27328425

MLST8:​MTOR:​RPTOR|​unk@Nucleus

Identifiers
NAME:MLST8:MTOR:RPTOR

References
rc_re888( Regulated Cell Death  map ):
PMID:16915281
in mouse, PML directs mTOR to the nucleus, thereby inhibiting its interaction with Rheb and its ability to promote HIF1A translation

MLST8:​MTOR:​RPTOR|​unk@PML Body

Identifiers
NAME:MLST8:MTOR:RPTOR

References
rc_re888( Regulated Cell Death  map ):
PMID:16915281
in mouse, PML directs mTOR to the nucleus, thereby inhibiting its interaction with Rheb and its ability to promote HIF1A translation

(MLST8:​MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm

Identifiers
NAME:MLST8:MTOR:RPTOR

References
s_akt1_re65:( Survival  map ) PMID:16286006
s_akt1_re193:( Survival  map ) PMID:20932932

MLST8:​MTOR|​S2448_pho:​RPTOR@Lysosome

Identifiers
NAME:MLST8:MTOR:RPTOR

References
mo_re189:( motility  map ) PMID:26597054 PMID:27328425
mo_re152:( motility  map ) PMID:19930715 PMID:26597054 PMID:27572739 PMID:27510662
mo_re251:( motility  map ) PMID:27328425 PMID:27572739 PMID:27510662

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. (MLST8:​MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map
In compartment: Lysosome
  1. MLST8:​MTOR:​RPTOR@Lysosome map
  2. MLST8:​MTOR|​S2448_pho:​RPTOR@Lysosome map
In compartment: Nucleus
  1. MLST8:​MTOR:​RPTOR|​unk@Nucleus map
In compartment: PML Body
  1. MLST8:​MTOR:​RPTOR|​unk@PML Body map
Participates in reactions:
As Reactant or Product:
  1. GDP:​GTP:​MLST8:​MTOR:​RPTOR:​Rag A/B*:​Rag C/D*@Lysosome map → map GDP:​GTP:​Rag A/B*:​Rag C/D*@Lysosome map + MLST8:​MTOR:​RPTOR@Lysosome map
  2. MLST8:​MTOR:​RPTOR@Lysosome map → map MLST8:​MTOR|​S2448_pho:​RPTOR@Lysosome map
  3. rc_s7967 → map MLST8:​MTOR:​RPTOR|​unk@Nucleus map
  4. MLST8:​MTOR:​RPTOR|​unk@Nucleus map → map MLST8:​MTOR:​RPTOR|​unk@PML Body map
  5. YY1@Nucleus map + PPARGC1A@Nucleus map + MLST8:​MTOR:​RPTOR|​unk@Nucleus map → map MLST8:​MTOR:​PPARGC1A:​RPTOR|​pho:​YY1@Nucleus map
  6. MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map → map (MLST8:​MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map
As Catalyser:
  1. gMMP2@Nucleus map → map rMMP2@Nucleus map
  2. 4E-BP1@Cytosol map → map 4E-BP1|​pho@Cytosol map
  3. S6K*@Cytosol map → map S6K*|​pho@Cytosol map
  4. gMMP9@Nucleus map → map rMMP9@Nucleus map
  5. p70_beta_*@Cytoplasm map → map p70_beta_*|​T388_pho@Cytoplasm map
  6. (MLST8:​MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map + 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​mRNA generic*:​p70_alpha_*@Cytoplasm map → map 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map