Reaction known_transition_omitted em_emtc_emtc_re761 map

PAK*@Cytosol map → PAK*|​pho|​active@Cytosol map

Reaction regulators:
Physical_stimulation
  1. GTP:​RAC1@Cytosol map


References
PMID:8805275
PMID:8910277
PMID:9744077
PMID:10023776
PMID:11728826
GTP-bound Rac1 activates PAK1,2,3.
The binding of the active GTP form of Rac1 and the PBD domain of PAK1,2,3 promotes autophosphorylation of PAK1,2,3 and activation of JNK pathway.