Protein ATP6V0C_D* map

Identifiers
ATPase H+ transporting lysosomal 16kDa V0 subunit c
HUGO:ATP6V0C HGNC:855 ENTREZ:527 UNIPROT:P27449 GENECARDS:ATP6V0C REACTOME:67124 KEGG:527 ATLASONC:GC_ATP6V0C WIKI:ATP6V0C
ATPase H+ transporting lysosomal 38kDa V0 subunit d1
HUGO:ATP6V0D1 HGNC:13724 ENTREZ:9114 UNIPROT:P61421 GENECARDS:ATP6V0D1 REACTOME:67070 KEGG:9114 WIKI:ATP6V0D1
ATPase H+ transporting lysosomal 38kDa V0 subunit d2
HUGO/ATP6V0D2 HGNC:18266 ENTREZ:245972 UNIPROT:Q8N8Y2
HUGO:ATP6VOC GENECARDS:ATP6VOC WIKI:ATP6VOC HUGO:ATP6V0C HGNC:855 ENTREZ:527 UNIPROT:P27449 GENECARDS:ATP6V0C REACTOME:67124 KEGG:527 ATLASONC:GC_ATP6V0C WIKI:ATP6V0C
ATP6D, "ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D", "ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1", "ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D1"
HUOG:ATP6V0D1 HGNC:13724 ENTREZ:9114 UNIPROT:P61421
HUGO:ATP6V0D2 HGNC:18266 ENTREZ:245972 UNIPROT:Q8N8Y2 GENECARDS:ATP6V0D2 REACTOME:254033 KEGG:245972 WIKI:ATP6V0D2

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:20093472

ATP6V0C_D*@Endosome

References
s_wnc1_re105( Survival  map ):
Acidification of the endosome is required for transducing the signal. The exact mechanism is unknown except that v-ATPase is involved in the process.
PMID:20699474
PMID:21380625
s_wnc1_re119( Survival  map ):
PRR binds to subunits ATP6V0C/D of the ATPase to lower the pH in the endosome. The reason for this is unknown but it is speculated that a lower pH is required for remodeling of the actin skeleton. However, v-ATPase is necessary for signaling
PMID:21796133
PMID:20093472
su_wnc1_s_wnc1_re119( Survival  map ):

ATP6V0C_D*@Cytoplasm

References
s_wnc1_re119( Survival  map ):
PRR binds to subunits ATP6V0C/D of the ATPase to lower the pH in the endosome. The reason for this is unknown but it is speculated that a lower pH is required for remodeling of the actin skeleton. However, v-ATPase is necessary for signaling
PMID:21796133
PMID:21380625
PMID:20093472

ATP6V0C_D*@Endosome

References
s_wnc1_re137( Survival  map ):
Acidification of the endosome is required for transducing the signal. The exact mechanism is unknown except that v-ATPase is involved in the process.
PMID:20699474
PMID:21380625

ATP6V0C_D*@Vaceolae

References
s_wca1_re68( Survival  map ):
PMID:20093472
PRR binds to subunits ATP6V0C and D those are subunits of the V-ATPase.

Modifications:
In compartment: Cytoplasm
  1. ATP6V0C_D*@Cytoplasm map
In compartment: Endosome
  1. ATP6V0C_D*@Endosome map
  2. ATP6V0C_D*@Endosome map
In compartment: Vaceolae
  1. ATP6V0C_D*@Vaceolae map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ATP6V0C_D*@Vaceolae map → map ATP6V0C_D*@Vaceolae map
    2. ATP6V0C_D*@Endosome map → map ATP6V0C_D*@Endosome map
    3. ATP6V0C_D*@Cytoplasm map → map ATP6V0C_D*@Endosome map
    4. ATP6V0C_D*@Endosome map → map ATP6V0C_D*@Endosome map
    5. ATP6V0C_D*@Cytoplasm map → map ATP6V0C_D*@Endosome map
    As Catalyser:
    1. H+@Cytoplasm map → map H+@Vaceolae map
    2. H+@Endosome map → map H+@Endosome map
    3. H+@Cytoplasm map → map H+@Endosome map