Complex DVL*:G_beta_*:G_gamma_*:_beta_-Arrestin2*
Complex composition:
- G_gamma_*
- G_beta_*
- DVL*
- _beta_-Arrestin2*
DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
Identifiers
NAME:DVL*:G_beta_*:G_gamma_*:_beta_-Arrestin2*
References
s_wca1_re29( Survival
):
PMID:19705439 PMID:17426148
Beta-ARRESTIN binds to phosphorylated DVL
s_wca1_re28( Survival
):
PMID:20006983 PMID:16965538 PMID:210606194 PMID:20093472 PMID:21796133
Phosphorylation of DVL by CK1 epsilon. Activation of CK1 epsilon by unknown factor
An acidic environment is required for phosphorylation of DVL and LRP5/6
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
Participates in reactions:
As Reactant or Product:- DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ AMER1*:CK1_gamma_*:PtdIns(4,5)-P2@Cytoplasm
→
AMER1*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:_beta_-Arrestin2*:p120*@Vaceolae
+ GTP:G_alpha_o*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
- DVL*|pho|emp|emp@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
+ _beta_-Arrestin2*@Cytoplasm
→
DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
As Catalyser: