Complex GTP:RHEB
Complex composition:
- RHEB
- GTP
(GTP:RHEB)|active@T_cell
Identifiers
NAME:GTP:RHEB
References
PMID:12906785 PMID:19022819
GTP:RHEB@Lysosome
Identifiers
NAME:GTP:RHEB
References
mo_re183:( motility
) PMID:26597054
mo_re184:( motility
) PMID:26597054 PMID:27328425
(GTP:RHEB)|active@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:GTP:RHEB
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
DENDRITIC_CELL
NATURAL_KILLER
CASCADE:IL15
CASCADE:CSF2
PMID:12906785, PMID:19022819
AKT activates Rapamycin associated protein FRAP2 ( mTOR ) probably through Tuberin/GTP-binding protein Ras homolog enriched in brain ( RHEB ) pathway.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- (GTP:RHEB)|active@INNATE_IMMUNE_CELL_Cytosol
In compartment: Lysosome
- GTP:RHEB@Lysosome
In compartment: T_cell
- (GTP:RHEB)|active@T_cell
Participates in reactions:
As Reactant or Product:- (GTP:RHEB)|active@T_cell
+ GDP@T_cell
→
GDP:RHEB@T_cell
+ GTP@T_cell
- (GTP:RHEB)|active@INNATE_IMMUNE_CELL_Cytosol
+ GDP@INNATE_IMMUNE_CELL_Cytosol
→
GDP:RHEB@INNATE_IMMUNE_CELL_Cytosol
+ GTP@INNATE_IMMUNE_CELL_Cytosol
- GDP:RHEB@Lysosome
→
GTP:RHEB@Lysosome
- GTP:RHEB@Lysosome
→
GDP:RHEB@Lysosome
As Catalyser:- DEPTOR:MLST8:MTOR:PRAS40*:RPTOR@T_cell
→
(DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@T_cell
- DEPTOR:MLST8:MTOR:PRAS40*:RPTOR@INNATE_IMMUNE_CELL_Cytosol
→
(DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@INNATE_IMMUNE_CELL_Cytosol
- MLST8:MTOR:RPTOR@Lysosome
→
MLST8:MTOR|S2448_pho:RPTOR@Lysosome