Reaction heterodimer_association su_wca1_s_wca2_re72
E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
+ CRIPTO-1*:LRP5_6*@Cytoplasm
→ CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
No reaction regulators
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
Upon WNT3a CRIPTO-1 binds to LRP5/6 this binding is competing with DKK binding
PMID:23022962