Reaction dissociation su_wca1_s_wca2_re21
E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→ LRP5_6*@Cytoplasm
+ E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
Reaction regulators:
- Catalysis
- DKK1@default
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
DKK1 can disrupt binding of Fz/LRP6/WNT complex
PMID:11448771