Simple molecule cAMP
cAMP@T_cell
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ INHIBITING_CHECKPOINTS
cAMP@Cytosol
Identifiers
CHEBI:17489
References
rc_re1860( Regulated Cell Death
):
PMID:19942859
Lipolityc signal induce PKA activation that leads to AMPK activation and so lipid resynthesis
cAMP@INNATE_IMMUNE_CELL_Cytosol
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity
/ IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
References
PMID:7890616
Intracellular Ca2+??release induces cAMP Accumulation in Human Monocytes and activation of PKA signaling downstream of IL13.
Modifications:
In compartment: Cytoplasm
- cAMP@Cytoplasm
In compartment: Cytosol
- cAMP@Cytosol
In compartment: INNATE_IMMUNE_CELL_Cytosol
- cAMP@INNATE_IMMUNE_CELL_Cytosol
In compartment: T_cell
- cAMP@T_cell
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- PKA_R*:cAMP@INNATE_IMMUNE_CELL_Cytosol
- PKA*:PKA_R*:cAMP@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- ATP@T_cell
→
cAMP@T_cell
- ATP@INNATE_IMMUNE_CELL_Cytosol
→
cAMP@INNATE_IMMUNE_CELL_Cytosol
- cAMP@INNATE_IMMUNE_CELL_Cytosol
+ PKA*:PKA_R*@INNATE_IMMUNE_CELL_Cytosol
→
PKA*:PKA_R*:cAMP@INNATE_IMMUNE_CELL_Cytosol
- PKA*:PKA_R*:cAMP@INNATE_IMMUNE_CELL_Cytosol
→
PKA_R*:cAMP@INNATE_IMMUNE_CELL_Cytosol
+ PKA*@INNATE_IMMUNE_CELL_Cytosol
- ATP@Cytoplasm
→
cAMP@Cytoplasm
As Catalyser:- PKA*|hm2:PKA1_R|hm2@T_cell
→
PKA1_R|hm2@T_cell
+ PKA*|hm2|active@T_cell
- PKA_C*@Cytosol
→
PKA_C*@Cytosol
- PKA_C*:PKA_R*@Cytoplasm
→
PKA_C*:PKA_R*@Cytoplasm