Complex CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT* map
Complex composition:

  1. CRIPTO-1* map
  2. LRP5_6* map
  3. FZD* map
  4. WNT* map
  5. E-Cadherin* map
  6. G_alpha_o* map
  7. G_beta_* map
  8. G_gamma_* map
  9. GTP map


CRIPTO-1*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*@Cytoplasm

Identifiers
NAME:CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
s_wca2_re72( Survival  map ):
Upon WNT3a CRIPTO-1 binds to LRP5/6 this binding is competing with DKK binding
PMID:23022962
s_wca2_re71( Survival  map ):
Binding of CRIPTO-1 to LRP5/6 enhances Topflash activity
su_wca1_s_wca2_re71( Survival  map ):


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. CRIPTO-1*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. CRIPTO-1*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*@Cytoplasm map map WNT canonical pathway@Cytoplasm map
  2. E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​WNT*@Cytoplasm map + CRIPTO-1*:​LRP5_6*@Cytoplasm map map CRIPTO-1*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*@Cytoplasm map
As Catalyser: