Protein p120* map

Identifiers
catenin (cadherin-associated protein), delta 1
HUGO:CTNND1 HGNC:2515 ENTREZ:1500 UNIPROT:O60716
HUGO:CTNND1 HGNC:2515 ENTREZ:1500 UNIPROT:O60716 GENECARDS:CTNND1 REACTOME:52998 KEGG:1500 ATLASONC:CTNND1ID40197ch11q11 WIKI:CTNND1
catenin (cadherin-associated protein) delta 2 (neural plakophilin-related arm-repeat protein)
HUGO:CTNND2 HGNC:2516 ENTREZ:1501 UNIPROT:Q9UQB3 GENECARDS:CTNND2 KEGG:1501 ATLASONC:GC_CTNND2 WIKI:CTNND2
catenin (cadherin-associated protein) delta 2

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / ADHERENS_JUNCTIONS  map
 EMT Senescence  map  / LYSOSOME_ENDOSOME  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:12426320
VE-cadhein interacts with catenin delta 1 (p120-catenin, CTNND1)
PMID:19029934

p120*@Cytosol

References
em_emtc_emtc_re1026( EMT Senescence  map ):
PMID:15609097
CTNNB1 (beta-catenin) binds with high affinity to the distal Cadherin cytoplasmic tail.
Cadherin recruits CTNNA1 (alpha-catenin) to the complex.
CTNNA1 (alpha-catenin) binds to Actin filaments directly
CTNNA1 (alpha-catenin) and can also associate with other actin-binding proteins (MLLT4 or Formin)
CTNND1 (delta-catenin or p120) binds directly to Cadherin independently of the other catenins.
Catenins/Cadherin complex can further interact with a range of singaling molecules which participate in either cellular signaling or control of cytoskeletal dynamics.
Stability of Cadherin/Catenins complex and thereby the integrity of adherens junctions is controlled by phosphorylation/dephosphorylation.

p120*@Clathrin coated vesicle

References
em_re1456( EMT Senescence  map ):
PMID??:10402472
We conclude that a pool of surface E-cadherin is constantly trafficked through an endocytic, recycling pathway and that this may provide a mechanism for regulating the availability of E-cadherin for junction formation in development, tissue remodeling, and tumorigenesis.

p120*@Cytoplasm

References
su_wnc1_s_wnc4_re31( Survival  map ):
binding of G-alpha12 toE-cadherin results of loss of binding of b-catenin from the adherence junction
PMID:11136230
su_wnc1_s_wnc4_re24( Survival  map ):
Complex of G-alpha12 and p120 stabilises binding of E-cadherin in Adhesion-complex. G-alpha12 is found back in complex with p120 and E-cadherin
PMID:15240885
su_wca1_s_wca2_re50:( Survival  map ) PMID:22659456 PMID:22007144 PMID:19171760 PMID:10931041

p120*@Cytoplasm

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
s_wnc4_re31( Survival  map ):
binding of G-alpha12 toE-cadherin results of loss of binding of b-catenin from the adherence junction
PMID:11136230
s_wca2_re50:( Survival  map ) PMID:22659456 PMID:22007144 PMID:19171760 PMID:10931041
s_wnc4_re24( Survival  map ):
Complex of G-alpha12 and p120 stabilises binding of E-cadherin in Adhesion-complex. G-alpha12 is found back in complex with p120 and E-cadherin
PMID:15240885

Modifications:
In compartment: Clathrin coated vesicle
  1. p120*@Clathrin coated vesicle map
In compartment: Cytoplasm
  1. p120*@Cytoplasm map
  2. p120*@Cytoplasm map
In compartment: Cytosol
  1. p120*@Cytosol map
In compartment: Endosome
  1. p120*@Endosome map
In compartment: Lysosome
  1. p120*@Lysosome map
Participates in complexes:
In compartment: Cytoplasm
  1. G_alpha__sub_12_endsub_*:​p120*@Cytoplasm map
  2. E-Cadherin*:​_alpha_-Catenin*:​cytoskeleton:​p120*@Cytoplasm map
  3. Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytoplasm map
  4. Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*|​Y142_pho:​p120*@Cytoplasm map
  5. E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map
  6. Cytoskeleton:​E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ECM or cell-cell contact:​ITGA3:​_alpha_-Catenin*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map
  7. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*:​p120*@Cytoplasm map
  8. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
In compartment: Cytosol
  1. Cadherin*:​p120*@Cytosol map
  2. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map
In compartment: Endosome
  1. CK1_epsilon_*:​p120*|​S268_pho|​S269_pho@Endosome map
  2. E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​p120*@Endosome map
  3. E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Endosome map
  4. E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​Y654_pho|​pho:​p120*@Endosome map
  5. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  6. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  7. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  8. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  9. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*|​pho:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*|​S268_pho|​S269_pho@Endosome map
  10. AMER1*:​APC:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
In compartment: Vaceolae
  1. CK1_epsilon_*:​E-Cadherin*:​LRP5_6*:​p120*@Vaceolae map
  2. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​p120*@Vaceolae map
  3. AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map
  4. AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map
Participates in reactions:
As Reactant or Product:
  1. Catenin*@Cytosol map → map p120*@Cytosol map
  2. Cadherin*@Cytosol map + p120*@Cytosol map → map Cadherin*:​p120*@Cytosol map
  3. _beta_-Catenin*_p120*1_Plakoglobin*_Plakophilin4*@Cytosol map → map p120*@Cytosol map
  4. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*@Cytosol map + Cadherin*:​p120*@Cytosol map + Actin cytoskeletal*@Cytosol map → map Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map
  5. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map E-Cadherin*|​Y_pho@Cytosol map
  6. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map Adherens junctions@Cytosol map
  7. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map _alpha_-Catenin*@Clathrin coated vesicle map
  8. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map E-Cadherin*@Clathrin coated vesicle map
  9. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map _beta_-Catenin*@Clathrin coated vesicle map
  10. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map p120*@Clathrin coated vesicle map
  11. p120*@Clathrin coated vesicle map → map p120*@Endosome map
  12. p120*@Endosome map → map p120*@Lysosome map
  13. p120*@Lysosome map → map degraded
  14. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map E-Cadherin*@Caveolin vesicle map
  15. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map E-Cadherin*@Macropinosome map
  16. Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytosol map → map degraded
  17. WNT*@default map + CK1_epsilon_*:​E-Cadherin*:​LRP5_6*:​p120*@Vaceolae map + FZD*:​GDP:​G_alpha_o*:​G_beta_*:​G_gamma_*@Cytoplasm map + GTP@Vaceolae map + PRR*@Cytoplasm map → map CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​p120*@Vaceolae map + GDP@Vaceolae map
  18. DVL*|​pho|​emp|​emp:​G_beta_*:​G_gamma_*:​_beta_-Arrestin2*@Cytoplasm map + CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​p120*@Vaceolae map + AMER1*:​CK1_gamma_*:​PtdIns(4,5)-P2@Cytoplasm map → map AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map + GTP:​G_alpha_o*@Cytoplasm map + G_beta_*:​G_gamma_*@Cytoplasm map
  19. AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map → map AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map
  20. AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map + AXIN*:​CK1_alpha_*:​GSK3*:​G_alpha_o*:​_beta_-Arrestin2*@Cytoplasm map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  21. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  22. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map + AXIN*:​CK1_alpha_*:​GSK3*:​G_alpha_o*:​_beta_-Arrestin2*@Cytoplasm map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  23. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​APC:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  24. AMER1*:​APC:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  25. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*|​pho:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*|​S268_pho|​S269_pho@Endosome map
  26. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*|​pho:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*|​S268_pho|​S269_pho@Endosome map → map CK1_epsilon_*:​p120*|​S268_pho|​S269_pho@Endosome map + E-Cadherin*|​pho@Endosome map + AMER1*:​AXIN*:​CK1_alpha_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*@Endosome map
  27. Cytoskeleton:​E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ECM or cell-cell contact:​ITGA3:​_alpha_-Catenin*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map + TGFB1:​TGFBR*@Cytoplasm map → map E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map + ECM or cell-cell contact@default map
  28. E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map → map E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Endosome map
  29. E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​pho:​p120*@Endosome map → map E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​Y654_pho|​pho:​p120*@Endosome map
  30. E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​_beta_-Catenin*|​Y654_pho|​pho:​p120*@Endosome map → map E-Cadherin*:​ITGA3:​TGFB1:​TGFBR*:​p120*@Endosome map + _beta_-Catenin*|​Y654_pho@Cytoplasm map
  31. ECM or cell-cell contact@default map + E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho@Cytoplasm map + p120*@Cytoplasm map + ITGA3@Cytoplasm map + Cytoskeleton@Cytoplasm map + _alpha_-Catenin*@Cytoplasm map + _beta_-Catenin*|​pho@Cytoplasm map → map Cytoskeleton:​E-Cadherin*|​S840_pho|​S853_pho|​S855_pho|​S849_pho:​ECM or cell-cell contact:​ITGA3:​_alpha_-Catenin*:​_beta_-Catenin*|​pho:​p120*@Cytoplasm map
  32. LGR5:​RSPO1-4*@Cytoplasm map + CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*:​p120*@Cytoplasm map → map CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
  33. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map → map WNT canonical pathway@Cytoplasm map
  34. E-Cadherin*@Cytoplasm map + p120*@Cytoplasm map + _alpha_-Catenin*@Cytoplasm map + _beta_-Catenin*@Cytoplasm map + Cytoskeleton@Cytoplasm map → map Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytoplasm map
  35. p120*@Cytoplasm map + G_alpha__sub_12_endsub_*@Cytoplasm map → map G_alpha__sub_12_endsub_*:​p120*@Cytoplasm map
  36. Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytoplasm map → map _beta_-Catenin*@Cytoplasm map + p120*@Cytoplasm map + E-Cadherin*@Cytoplasm map + _alpha_-Catenin*@Cytoplasm map
  37. Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytoplasm map → map Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*|​Y142_pho:​p120*@Cytoplasm map
  38. Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*|​Y142_pho:​p120*@Cytoplasm map → map _beta_-Catenin*|​Y142_pho@Cytoplasm map + E-Cadherin*:​_alpha_-Catenin*:​cytoskeleton:​p120*@Cytoplasm map
As Catalyser:
  1. AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map → map AMER1*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Vaceolae map
  2. AMER1*:​APC:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map
  3. AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*@Endosome map → map AMER1*:​AXIN*:​CK1_alpha_*:​CK1_epsilon_*:​CK1_gamma_*:​DVL*|​pho|​pho|​pho:​E-Cadherin*|​pho:​FZD*:​GSK3*:​G_alpha_o*:​G_beta_*:​G_gamma_*:​LRP5_6*|​T1479_pho|​S1490_pho|​T1493_pho|​S1496_pho|​T1530_pho|​S1533_pho:​PRR*:​WNT*:​_beta_-Arrestin2*:​p120*|​S268_pho|​S269_pho@Endosome map
  4. DVL*@Cytoplasm map + CUL3:​KLHL*:​RBX1@Cytoplasm map → map CUL3:​DVL*:​KLHL*:​RBX1@Cytoplasm map
  5. JBN*:​_beta_-Catenin*@Cytoplasm map → map JBN*:​_beta_-Catenin*@Cilium map
  6. JBN*:​_beta_-Catenin*@Cilium map → map su_wca1_s_wca1_s764
  7. ATP6V0C_D*@Vaceolae map → map ATP6V0C_D*@Vaceolae map
  8. SRC@Cytoplasm map → map SRC@Cytoplasm map
  9. E-Cadherin*@Cytoplasm map + p120*@Cytoplasm map + _alpha_-Catenin*@Cytoplasm map + _beta_-Catenin*@Cytoplasm map + Cytoskeleton@Cytoplasm map → map Cytoskeleton:​E-Cadherin*:​_alpha_-Catenin*:​_beta_-Catenin*:​p120*@Cytoplasm map