References
su_wnc1_s_wnc4_re24( Survival ):
Complex of G-alpha12 and p120 stabilises binding of E-cadherin in Adhesion-complex. G-alpha12 is found back in complex with p120 and E-cadherin
PMID:15240885
su_wca1_s_wca2_re50:( Survival ) PMID:22659456 PMID:22007144 PMID:19171760 PMID:10931041
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_CANONICAL
References
s_wca2_re50:( Survival ) PMID:22659456 PMID:22007144 PMID:19171760 PMID:10931041
s_wnc4_re24( Survival ):
Complex of G-alpha12 and p120 stabilises binding of E-cadherin in Adhesion-complex. G-alpha12 is found back in complex with p120 and E-cadherin
PMID:15240885
+ TGFB1:TGFBR*@Cytoplasm → E-Cadherin*|S840_pho|S853_pho|S855_pho|S849_pho:ITGA3:TGFB1:TGFBR*:_beta_-Catenin*|pho:p120*@Cytoplasm + ECM or cell-cell contact@default
+ E-Cadherin*|S840_pho|S853_pho|S855_pho|S849_pho@Cytoplasm + p120*@Cytoplasm + ITGA3@Cytoplasm + Cytoskeleton@Cytoplasm + _alpha_-Catenin*@Cytoplasm + _beta_-Catenin*|pho@Cytoplasm → Cytoskeleton:E-Cadherin*|S840_pho|S853_pho|S855_pho|S849_pho:ECM or cell-cell contact:ITGA3:_alpha_-Catenin*:_beta_-Catenin*|pho:p120*@Cytoplasm
+ p120*@Cytoplasm + _alpha_-Catenin*@Cytoplasm + _beta_-Catenin*@Cytoplasm + Cytoskeleton@Cytoplasm → Cytoskeleton:E-Cadherin*:_alpha_-Catenin*:_beta_-Catenin*:p120*@Cytoplasm
→ _beta_-Catenin*@Cytoplasm + p120*@Cytoplasm + E-Cadherin*@Cytoplasm + _alpha_-Catenin*@Cytoplasm
→ Cytoskeleton:E-Cadherin*:_alpha_-Catenin*:_beta_-Catenin*|Y142_pho:p120*@Cytoplasm
→ _beta_-Catenin*|Y142_pho@Cytoplasm + E-Cadherin*:_alpha_-Catenin*:cytoskeleton:p120*@Cytoplasm