Reaction heterodimer_association su_wnc1_s_wnc1_re109
APC2*:GSK3*@Cytoplasm
+ CK1_epsilon_*:CTHRC1:DVL*|pho|S142_pho|S139_pho:FZD*:PAR6*:PRR*:RACK1*:ROR2:RSPO3:SYN4*:VANGL*:WNT*:_beta_-Arrestin2*@Endosome
→ APC2*:CK1_epsilon_*:CTHRC1:DVL*|pho|S142_pho|S139_pho:FZD*:GSK3*:PAR6*:PRR*:RACK1*:ROR2|S864_pho:RSPO3:SYN4*:VANGL*:WNT*:_beta_-Arrestin2*@Endosome
No reaction regulators
References
Polymerised Dvl act as scaffold for recruiting axin.
PMID:21078818
GSK3 phosphorylates ROR2
PMID:17986005