Protein PRICKLE1 map

Identifiers
prickle homolog 1 (Drosophila)
"prickle-like 1 (Drosophila)"
HUGO:PRICKLE1 HGNC:17019 ENTREZ:144165 UNIPROT:Q96MT3 GENECARDS:PRICKLE1 KEGG:144165 ATLASONC:GC_PRICKLE1 WIKI:PRICKLE1

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
Prickle is actually associated with membrane

PRICKLE1@Cytoplasm

References
s_wnc1_re78:( Survival  map ) PMID:22037766

PRICKLE1|​pho@Cytoplasm

References
s_wnc1_re78:( Survival  map ) PMID:22037766
s_wnc1_re85( Survival  map ):
Prickle interacts physically with Vangl
PMID:22037766
PMID:12941693
Par6 is constitutively associated with Dvl
PMID:19379695

PRICKLE1|​pho|​ubi@Cytoplasm

References
s_wnc1_re111( Survival  map ):
Rspo is required for clathrin-mediated endocytosis
PMID:21397842
It has been shown that Dvl polymers are not associated with vesicles, therefore endocytosis of the complex is likely to be after Dvl polymerisation.
PMID:16263762
s_wnc1_re90( Survival  map ):
PMID:19379695
PMID:20930545

Modifications:
In compartment: Cytoplasm
  1. PRICKLE1@Cytoplasm map
  2. PRICKLE1|​pho@Cytoplasm map
  3. PRICKLE1|​pho|​ubi@Cytoplasm map
Participates in complexes:
In compartment: Cytoplasm
  1. PAR6*:​PRICKLE1|​pho:​RACK1*:​VANGL*@Cytoplasm map
  2. CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map
  3. CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​RACK1*:​ROR2|​S864_emp|​emp|​emp:​SYN4*:​VANGL*|​emp|​emp|​emp|​emp:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  4. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​RACK1*:​ROR2|​S864_emp|​emp|​emp:​SYN4*:​VANGL*|​emp|​emp|​emp|​emp:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  5. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  6. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  7. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho|​ubi:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  8. CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho|​ubi:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map + RSPO3@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRR*:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map + SMURF1@Cytoplasm map + PRICKLE1|​pho|​ubi@Cytoplasm map
  2. ROR2@Cytoplasm map + FZD*:​GDP:​G_alpha_*:​G_beta_*:​G_gamma_*@Cytoplasm map + WNT*@default map + GTP@Cytoplasm map + CK1_epsilon_*@Cytoplasm map + CTHRC1@Cytoplasm map + SYN4*@Cytoplasm map + PAR6*:​PRICKLE1|​pho:​RACK1*:​VANGL*@Cytoplasm map + PRR*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map + GDP@Cytoplasm map
  3. CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map → map GTP:​G_alpha_*@Cytoplasm map + CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map + G_beta_*:​G_gamma_*@Cytoplasm map
  4. CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map + DVL*|​pho|​S142_emp|​S139_emp:​_beta_-Arrestin2*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  5. PRICKLE1@Cytoplasm map → map PRICKLE1|​pho@Cytoplasm map
  6. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​RACK1*:​ROR2|​S864_emp|​emp|​emp:​SYN4*:​VANGL*|​emp|​emp|​emp|​emp:​WNT*:​_beta_-Arrestin2*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​RACK1*:​ROR2|​S864_emp|​emp|​emp:​SYN4*:​VANGL*|​emp|​emp|​emp|​emp:​WNT*:​_beta_-Arrestin2*@Cytoplasm map + DVL*|​pho|​S142_emp|​S139_emp|​ubi@Cytoplasm map
  7. RACK1*:​VANGL*@Cytoplasm map + PRICKLE1|​pho@Cytoplasm map + PAR6*@Cytoplasm map → map PAR6*:​PRICKLE1|​pho:​RACK1*:​VANGL*@Cytoplasm map
  8. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​RACK1*:​ROR2|​S864_emp|​emp|​emp:​SYN4*:​VANGL*|​emp|​emp|​emp|​emp:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  9. SMURF1@Cytoplasm map + CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  10. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​S142_emp|​S139_emp:​FZD*:​PAR6*:​PRICKLE1|​pho|​ubi:​PRR*:​RACK1*:​ROR2:​SMURF1:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Cytoplasm map
  11. PRICKLE1|​pho|​ubi@Cytoplasm map → map degraded
As Catalyser: