Identifiers
guanine nucleotide binding protein (G protein) alpha 11 (Gq class)
HUGO:GNA11 HGNC:4379 ENTREZ:2767 UNIPROT:P29992 GENECARDS:GNA11 REACTOME:55354 KEGG:2767 ATLASONC:GNA11ID43272ch19p13 WIKI:GNA11
guanine nucleotide binding protein (G protein) alpha 12
HUGO:GNA12 HGNC:4380 ENTREZ:2768 UNIPROT:Q03113 GENECARDS:GNA12 REACTOME:55356 KEGG:2768 ATLASONC:GC_GNA12 WIKI:GNA12
guanine nucleotide binding protein (G protein) alpha 13
HUGO:GNA13 HGNC:4381 ENTREZ:10672 UNIPROT:Q14344 GENECARDS:GNA13 REACTOME:55358 KEGG:10672 ATLASONC:GC_GNA13 WIKI:GNA13
guanine nucleotide binding protein (G protein) alpha 14
HUGO:GNA14 HGNC:4382 ENTREZ:9630 UNIPROT:O95837 GENECARDS:GNA14 REACTOME:55360 ATLASONC:GC_GNA14 WIKI:GNA14
guanine nucleotide binding protein (G protein) alpha 15 (Gq class)
HUGO:GNA15 HGNC:4383 ENTREZ:2769 UNIPROT:P30679 GENECARDS:GNA15 REACTOME:55362 KEGG:2769 ATLASONC:GC_GNA15 WIKI:GNA15
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1
HUGO:GNAI1 HGNC:4384 ENTREZ:2770 UNIPROT:P63096 GENECARDS:GNAI1 REACTOME:55432 KEGG:2770 ATLASONC:GC_GNAI1 WIKI:GNAI1
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 2
HUGO:GNAI2 HGNC:4385 ENTREZ:2771 UNIPROT:P04899 GENECARDS:GNAI2 REACTOME:55436 KEGG:2771 ATLASONC:GC_GNAI2 WIKI:GNAI2
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3
HUGO:GNAI3 HGNC:4387 ENTREZ:2773 UNIPROT:P08754 GENECARDS:GNAI3 REACTOME:55366 KEGG:2773 ATLASONC:GC_GNAI3 WIKI:GNAI3
guanine nucleotide binding protein (G protein) alpha activating activity polypeptide olfactory type
HUGO:GNAL HGNC:4388 ENTREZ:2774 UNIPROT:P38405 GENECARDS:GNAL REACTOME:55364 ATLASONC:GC_GNAL WIKI:GNAL
guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O
HUGO:GNAO1 HGNC:4389 ENTREZ:2775 UNIPROT:P09471 GENECARDS:GNAO1 REACTOME:55350 KEGG:2775 ATLASONC:GC_GNAO1 WIKI:GNAO1
guanine nucleotide binding protein (G protein) q polypeptide
HUGO:GNAQ HGNC:4390 ENTREZ:2776 UNIPROT:P50148 GENECARDS:GNAQ REACTOME:55454 KEGG:2776 ATLASONC:GNAQID43280ch9q21 WIKI:GNAQ
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_CANONICAL
References
PMID:21640127
+ CK1_epsilon_*:E-Cadherin*:LRP5_6*:p120*@Vaceolae + FZD*:GDP:G_alpha_o*:G_beta_*:G_gamma_*@Cytoplasm + GTP@Vaceolae + PRR*@Cytoplasm → CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae + GDP@Vaceolae
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae + AMER1*:CK1_gamma_*:PtdIns(4,5)-P2@Cytoplasm → AMER1*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:_beta_-Arrestin2*:p120*@Vaceolae + GTP:G_alpha_o*@Cytoplasm + G_beta_*:G_gamma_*@Cytoplasm
+ AXIN*:CK1_alpha_*:GSK3*:G_alpha_o*:_beta_-Arrestin2*@Cytoplasm → AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
→ AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
+ AXIN*:CK1_alpha_*:GSK3*:G_alpha_o*:_beta_-Arrestin2*@Cytoplasm → AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
→ AMER1*:APC:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
→ AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
→ AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*|pho:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*|S268_pho|S269_pho@Endosome
→ CK1_epsilon_*:p120*|S268_pho|S269_pho@Endosome + E-Cadherin*|pho@Endosome + AMER1*:AXIN*:CK1_alpha_*:CK1_gamma_*:DVL*|pho|pho|pho:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*@Endosome
→ AMER1*:CK1_gamma_*:DVL*|pho|pho|pho|pho:FZD*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*@Endosome + AXIN*:CK1_alpha_*:GSK3*:G_alpha_o*:_beta_-Arrestin2*@Endosome
+ AXIN*:CK1_alpha_*:GSK3*@Cytoplasm + _beta_-Arrestin2*@Cytoplasm → AXIN*:CK1_alpha_*:GSK3*:G_alpha_o*:_beta_-Arrestin2*@Cytoplasm
→ Recycling @Cytoplasm
→ Degradation@Cytoplasm
→ GDP:G_alpha_o*@Cytoplasm + Pi@Cytoplasm
→ LRP5_6*@Cytoplasm + E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:WNT*@Cytoplasm
→ E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→ WNT canonical pathway@Cytoplasm
→ WNT canonical pathway@Cytoplasm
+ CRIPTO-1*:LRP5_6*@Cytoplasm → CRIPTO-1*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:WNT*@Cytoplasm
→ AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*@Endosome
→ AMER1*:AXIN*:CK1_alpha_*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*|pho:FZD*:GSK3*:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*|T1479_pho|S1490_pho|T1493_pho|S1496_pho|T1530_pho|S1533_pho:PRR*:WNT*:_beta_-Arrestin2*:p120*|S268_pho|S269_pho@Endosome
+ CUL3:KLHL*:RBX1@Cytoplasm → CUL3:DVL*:KLHL*:RBX1@Cytoplasm
→ JBN*:_beta_-Catenin*@Cilium
→ su_wca1_s_wca1_s764
→ ATP6V0C_D*@Vaceolae