Simple molecule 2-oxoglutarate map
2-oxoglutarate@Mitochondrial Matrix

Identifiers
CHEBI:16810 KEGGCOMPOUND:C00026 CAS:64-15-3

References
rc_re741( Regulated Cell Death  map ):
PMID:1457818
cloning of the human oxoglutarate-malate transporter

2-oxoglutarate@Cytosol

Identifiers
CHEBI:16810 KEGGCOMPOUND:C00026 CAS:64-15-3

2-oxoglutarate@Nucleus

Identifiers
CHEBI:16810 KEGGCOMPOUND:C00026 CAS:64-15-3

References
rc_re397( Regulated Cell Death  map ):
PMID:11641274
PMID:12080085
PMID:12042299
PMID:12215170
PMID:22841746

Modifications:
In compartment: Cytosol
  1. 2-oxoglutarate@Cytosol map
In compartment: Mitochondrial Matrix
  1. 2-oxoglutarate@Mitochondrial Matrix map
In compartment: Nucleus
  1. 2-oxoglutarate@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. 2-oxoglutarate:​CUL2:​O_sub_2_endsub_:​RACK1*:​RBX1:​TCEB1:​TCEB2:​VHL@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. 3-phosphonooxypyruvate@Cytosol map + L-glutamate@Cytosol map → map 3-P-serine@Cytosol map + 2-oxoglutarate@Cytosol map
  2. isocitrate@Cytosol map + NADP_super_+_endsuper_@Cytosol map → map 2-oxoglutarate@Cytosol map + CO_sub_2_endsub_@Cytosol map + NADPH@Cytosol map
  3. HIF1A@Cytosol map + 2-oxoglutarate:​CUL2:​O_sub_2_endsub_:​RACK1*:​RBX1:​TCEB1:​TCEB2:​VHL@Cytosol map + 2-oxoglutarate:​CUL2:​O_sub_2_endsub_:​RACK1*:​RBX1:​TCEB1:​TCEB2:​VHL@Cytosol map → map HIF1A|​P564_hyd@Cytosol map + succinate@Cytosol map + CO_sub_2_endsub_@Cytosol map
  4. HIF1A:​HIF1B*@Nucleus map + O_sub_2_endsub_@Nucleus map + 2-oxoglutarate@Nucleus map → map rc_s5678 + CO_sub_2_endsub_@Nucleus map + succinate@Nucleus map
  5. isocitrate@Mitochondrial Matrix map + H+@Mitochondrial Matrix map + NADP_super_+_endsuper_@Mitochondrial Matrix map → map 2-oxoglutarate@Mitochondrial Matrix map + CO_sub_2_endsub_@Mitochondrial Matrix map + NADPH@Mitochondrial Matrix map
  6. 2-oxoglutarate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map + NAD_super_+_endsuper_@Mitochondrial Matrix map → map succinyl-CoA@Mitochondrial Matrix map + H+@Mitochondrial Matrix map + CO_sub_2_endsub_@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map
  7. isocitrate@Mitochondrial Matrix map + H+@Mitochondrial Matrix map + NAD_super_+_endsuper_@Mitochondrial Matrix map → map 2-oxoglutarate@Mitochondrial Matrix map + CO_sub_2_endsub_@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map
  8. malate@Mitochondrial Matrix map + 2-oxoglutarate@Cytosol map → map malate@Cytosol map + 2-oxoglutarate@Mitochondrial Matrix map
  9. L-glutamate@Mitochondrial Matrix map + pyruvate@Mitochondrial Matrix map → map 2-oxoglutarate@Mitochondrial Matrix map + L-alanine@Mitochondrial Matrix map
  10. L-glutamate@Mitochondrial Matrix map + NAD_super_+_endsuper_@Mitochondrial Matrix map → map 2-oxoglutarate@Mitochondrial Matrix map + NH3@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map
As Catalyser:
  1. HIF1A|​P564_hyd@Cytosol map → map HIF1A|​ubi|​P564_hyd@Cytosol map