Phenotype ROS Production map
ROS Production@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / MITOCHONDRIAL_PERMEABILITY_TRANSITION  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
vicious cycles of damage favour the opening of the permeability-transition pore complex
increasing ROS production as a consequence of energy metabolism
PMID:19632174
PMID:20823910
PMID:18309324
PMID:27646922

Modifications:
In compartment: Cytosol
  1. ROS Production@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Glycogen breakdown@Cytosol map → map ROS Production@Cytosol map
    2. Glutaminolysis@Cytosol map → map ROS Production@Cytosol map
    3. FAD:​NOX*:​NOXA*:​NOXO*@Cytosol map → map ROS Production@Cytosol map
    4. ROS Production@Cytosol map → map PARP1 overactivation@Nucleus map
    5. AGEs@Cytosol map → map ROS Production@Cytosol map
    6. ROS production@Mitochondrial inner membrane map → map ROS Production@Cytosol map
    7. ROS Production@Cytosol map → map Necrosis death@Cytosol map
    8. STK11|​K48_unk|​T366_unk|​active@Cytosol map → map ROS Production@Cytosol map
    9. Glucose deprivation@Cytosol map → map ROS Production@Cytosol map
    10. Fe2+@Cytosol map → map ROS Production@Cytosol map
    11. ROS Production@Cytosol map → map Low AMP/ATP ratio@Cytosol map
    12. (ANT*:​CK*:​HK*:​PPID:​TSPO:​VDAC*)|​active@Mitochondrial inner membrane map → map ROS Production@Cytosol map
    13. ROS Production@Cytosol map → map ROS Production@Cytosol map
    14. ROS Production@Cytosol map → map NLRP3 activators@Extracellular space map
    As Catalyser:
    1. JNK*@Cytosol map → map JNK*|​Y185_pho@Cytosol map
    2. (ANT*:​CK*:​HK*:​PPID:​TSPO:​VDAC*)|​active@Mitochondrial inner membrane map → map (ANT*:​CK*:​HK*:​PPID:​TSPO:​VDAC*)|​active@Mitochondrial inner membrane map