Complex FMN:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFA1:NDUFA10:NDUFA11:NDUFA12:NDUFA13:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFAB1:NDUFB1:NDUFB10:NDUFB11:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFC1:NDUFC2:NDUFS1:NDUFS2:NDUFS3:NDUFS4:NDUFS5:NDUFS6:NDUFS7:NDUFS8:NDUFV1:NDUFV2:NDUFV3 map
Complex composition:

  1. NDUFS3 map
  2. MT-ND3 map
  3. MT-ND1 map
  4. MT-ND2 map
  5. MT-ND4 map
  6. MT-ND5 map
  7. MT-ND6 map
  8. NDUFA13 map
  9. NDUFA11 map
  10. NDUFA10 map
  11. NDUFA9 map
  12. NDUFS5 map
  13. NDUFS6 map
  14. NDUFB8 map
  15. NDUFB11 map
  16. NDUFB10 map
  17. NDUFAB1 map
  18. NDUFB7 map
  19. NDUFA12 map
  20. NDUFC2 map
  21. NDUFA6 map
  22. NDUFA5 map
  23. NDUFB3 map
  24. NDUFA3 map
  25. NDUFA2 map
  26. FMN map
  27. NDUFV1 map
  28. NDUFS7 map
  29. NDUFS1 map
  30. NDUFS2 map
  31. NDUFV2 map
  32. NDUFS8 map
  33. NDUFS4 map
  34. NDUFV3 map
  35. NDUFB2 map
  36. NDUFC1 map
  37. NDUFA4 map
  38. NDUFB1 map
  39. NDUFA1 map
  40. NDUFA8 map
  41. NDUFB5 map
  42. NDUFB6 map
  43. NDUFB4 map
  44. NDUFA7 map
  45. MT-ND4L map
  46. NDUFB9 map

FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane

Identifiers
NAME:FMN:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFA1:NDUFA10:NDUFA11:NDUFA12:NDUFA13:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFAB1:NDUFB1:NDUFB10:NDUFB11:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFC1:NDUFC2:NDUFS1:NDUFS2:NDUFS3:NDUFS4:NDUFS5:NDUFS6:NDUFS7:NDUFS8:NDUFV1:NDUFV2:NDUFV3

References
rc_re69( Regulated Cell Death  map ):
PMID:16200211
NDUFAF2
PMID:17344420
ECSIT:NDUFAF1
PMID:20816094
involvement of ACAD9 in the ECSIT:NDUFAF1 complex
PMID:16218961
NDUFAF1
PMID:15526035
AIF deficient cells exhibit a decrease content of complex I. It was proposed that AIF has a role in the biogenesis or maintenance of complex I
PMID:20025615
comprehensive review about complex I
rc_re68:( Regulated Cell Death  map ) PMID:18485875
rc_re70( Regulated Cell Death  map ):
PMID:19131594
in mouse liver, in mouse pro-B cells, STAT3 is found in mitochondria
mitochondrial STAT3 interacts with NDUFA13
mitochondrial STAT3 necessary for proper activity of complexes I and II of the electron transport chain
STAT3 in mitochondria is preferentially phosphorylated on S727
rc_re73:( Regulated Cell Death  map ) PMID:15807660
rc_re683:( Regulated Cell Death  map ) PMID:15186778

Modifications:
Participates in complexes:
In compartment: Mitochondrial inner membrane
  1. FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map
Participates in reactions:
As Reactant or Product:
  1. FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map → map cleaved~NDUFS3*@Mitochondrial intermembrane space map
  2. FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map → map cleaved~NDUFS1*@Mitochondrial intermembrane space map
  3. degraded + NDUFS8@Mitochondrial inner membrane map + MT-ND5@Mitochondrial inner membrane map + MT-ND4@Mitochondrial inner membrane map + MT-ND4L@Mitochondrial inner membrane map + MT-ND3@Mitochondrial inner membrane map + MT-ND2@Mitochondrial inner membrane map + MT-ND1@Mitochondrial inner membrane map + MT-ND6@Mitochondrial inner membrane map → map FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map
As Catalyser:
  1. ubiquinone@Mitochondrial inner membrane map + H+@Mitochondrial Matrix map + NADH@Mitochondrial Matrix map → map ubiquinol@Mitochondrial inner membrane map + H+@Mitochondrial intermembrane space map + NAD_super_+_endsuper_@Mitochondrial Matrix map
  2. NADH@Mitochondrial Matrix map + O_sub_2_endsub_@Mitochondrial Matrix map → map NAD_super_+_endsuper_@Mitochondrial Matrix map + O_sub_2_endsub__super_-_endsuper_@Mitochondrial Matrix map