Ion H+
H+@Cytosol
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ ANTIOXIDANT_RESPONSE
Regulated Cell Death
/ FERROPTOSIS
Regulated Cell Death
/ GLUCOSE_METABOLISM
H+@Vaceolae
References
s_wca1_re28( Survival
):
PMID:20006983 PMID:16965538 PMID:210606194 PMID:20093472 PMID:21796133
Phosphorylation of DVL by CK1 epsilon. Activation of CK1 epsilon by unknown factor
An acidic environment is required for phosphorylation of DVL and LRP5/6
Modifications:
In compartment: Cytoplasm
- H+@Cytoplasm
- H+@Cytoplasm
In compartment: Cytosol
- H+@Cytosol
In compartment: Endosome
- H+@Endosome
In compartment: Mitochondrial Matrix
- H+@Mitochondrial Matrix
In compartment: Mitochondrial intermembrane space
- H+@Mitochondrial intermembrane space
In compartment: Vaceolae
- H+@Vaceolae
Participates in complexes:
Participates in reactions:
As Reactant or Product:- glycerate-3P@Cytosol
+ NAD_super_+_endsuper_@Cytosol
→
3-phosphonooxypyruvate@Cytosol
+ NADH@Cytosol
+ H+@Cytosol
- pyruvate@Cytosol
+ NAD_super_+_endsuper_@Cytosol
→
lactate@Cytosol
+ NADH@Cytosol
+ H+@Cytosol
- glyceraldehyde-3P@Cytosol
+ NAD_super_+_endsuper_@Cytosol
→
glycerate-1,3P2@Cytosol
+ H+@Cytosol
+ NADH@Cytosol
- malate@Mitochondrial Matrix
+ NAD_super_+_endsuper_@Mitochondrial Matrix
→
oxaloacetate@Mitochondrial Matrix
+ H+@Mitochondrial Matrix
+ NADH@Mitochondrial Matrix
- isocitrate@Mitochondrial Matrix
+ H+@Mitochondrial Matrix
+ NADP_super_+_endsuper_@Mitochondrial Matrix
→
2-oxoglutarate@Mitochondrial Matrix
+ CO_sub_2_endsub_@Mitochondrial Matrix
+ NADPH@Mitochondrial Matrix
- 2-oxoglutarate@Mitochondrial Matrix
+ coenzyme A@Mitochondrial Matrix
+ NAD_super_+_endsuper_@Mitochondrial Matrix
→
succinyl-CoA@Mitochondrial Matrix
+ H+@Mitochondrial Matrix
+ CO_sub_2_endsub_@Mitochondrial Matrix
+ NADH@Mitochondrial Matrix
- isocitrate@Mitochondrial Matrix
+ H+@Mitochondrial Matrix
+ NAD_super_+_endsuper_@Mitochondrial Matrix
→
2-oxoglutarate@Mitochondrial Matrix
+ CO_sub_2_endsub_@Mitochondrial Matrix
+ NADH@Mitochondrial Matrix
- pyruvate@Mitochondrial Matrix
+ coenzyme A@Mitochondrial Matrix
+ NAD_super_+_endsuper_@Mitochondrial Matrix
→
acetyl-CoA@Mitochondrial Matrix
+ NADH@Mitochondrial Matrix
+ CO_sub_2_endsub_@Mitochondrial Matrix
+ H+@Mitochondrial Matrix
- ubiquinone@Mitochondrial inner membrane
+ H+@Mitochondrial Matrix
+ NADH@Mitochondrial Matrix
→
ubiquinol@Mitochondrial inner membrane
+ H+@Mitochondrial intermembrane space
+ NAD_super_+_endsuper_@Mitochondrial Matrix
- protoporphyrin IX@Mitochondrial intermembrane space
+ Fe2+@Mitochondrial intermembrane space
→
ferroheme b@Mitochondrial intermembrane space
+ H+@Mitochondrial intermembrane space
- Cytochrome_C*|ferriheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial Matrix
+ ubiquinol@Mitochondrial inner membrane
→
Cytochrome_C*|ferroheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial intermembrane space
+ ubiquinone@Mitochondrial inner membrane
- Cytochrome_C*|ferroheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial Matrix
+ O_sub_2_endsub_@Mitochondrial inner membrane
→
Cytochrome_C*|ferriheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial intermembrane space
- H+@Mitochondrial intermembrane space
+ ADP@Mitochondrial Matrix
→
H+@Mitochondrial Matrix
+ ATP@Mitochondrial Matrix
- H+@Mitochondrial Matrix
+ ATP@Mitochondrial Matrix
→
H+@Mitochondrial intermembrane space
+ ADP@Mitochondrial Matrix
- H+@Mitochondrial intermembrane space
→
H+@Mitochondrial Matrix
- H+@Cytoplasm
→
H+@Vaceolae
- H+@Endosome
→
H+@Endosome
- H+@Cytoplasm
→
H+@Endosome
As Catalyser:- DVL*|pho|emp|emp:G_beta_*:G_gamma_*:_beta_-Arrestin2*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ AMER1*:CK1_gamma_*:PtdIns(4,5)-P2@Cytoplasm
→
AMER1*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|pho|pho:E-Cadherin*:FZD*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:_beta_-Arrestin2*:p120*@Vaceolae
+ GTP:G_alpha_o*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm