Protein CDK1 map

Identifiers
HUGO:CDK1
cyclin-dependent kinase 1
HUGO:CDK1, HGNC:1722, ENTREZ:983, UNIPROT:P06493, GENECARDS:CDK1
HUGO:CDK1, HGNC:1722, ENTREZ:983, UNIPROT:P06493
HUGO:CDK1 HGNC:1722 ENTREZ:983 UNIPROT:P06493 GENECARDS:CDK1 REACTOME:86981 KEGG:983 ATLASONC:GC_CDK1 WIKI:CDK1

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / S_CC_PHASE  map
 Cell Cycle DNA Repair  map  / G2_CC_PHASE  map
 Cell Cycle DNA Repair  map  / M_CC_PHASE  map
 Cell Cycle DNA Repair  map  / G2_M_CHECKPOINT  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786
synonym:CDC2
PMID:14551205
PMID:18414028

CDK1|​Tyr15_pho|​Thr14_pho@Cytosol

References
mo_re84:( motility  map ) PMID:21725609

CDK1@Cytosol

References
mo_re84:( motility  map ) PMID:21725609

CDK1@Nucleus

References
te_re9:( Telomere Maintenance  map ) PMID:18625707, PMID:22624377

CDK1@Cytoplasm

References
s_akt1_re170:( Survival  map ) PMID:14551205

Modifications:
In compartment: Cytoplasm
  1. CDK1@Cytoplasm map
In compartment: Cytosol
  1. CDK1@Cytosol map
  2. CDK1|​Tyr15_pho|​Thr14_pho@Cytosol map
In compartment: Nucleus
  1. CDK1@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. CDK1:​CyclinB1*@Cytosol map
In compartment: Nucleus
  1. CDK1:​CyclinA1*@Nucleus map
  2. CDK1:​CyclinB1*@Nucleus map
  3. CDK1|​T161_pho:​CyclinB1*@Nucleus map
  4. CDK1|​T161_pho:​CyclinB1*@Nucleus map
  5. CDK1|​Y14/15_pho:​CyclinA1*@Nucleus map
  6. CDK1|​Y14/15_pho:​CyclinB1*@Nucleus map
  7. CDK1|​T161_pho|​pho:​CyclinB1*@Nucleus map
  8. CDK1|​Y14/15_pho|​T161_pho:​CyclinB1*@Nucleus map
  9. (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map
  10. CDK1:​CyclinB1*:​GADD45A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. CDK1@Nucleus map + CyclinB1*@Nucleus map → map CDK1:​CyclinB1*@Nucleus map
  2. CDK1:​CyclinB1*@Nucleus map → map CDK1|​Y14/15_pho:​CyclinB1*@Nucleus map
  3. CDK1|​Y14/15_pho|​T161_pho:​CyclinB1*@Nucleus map → map CDK1|​T161_pho:​CyclinB1*@Nucleus map
  4. CDK1:​CyclinB1*@Nucleus map → map CDK1@Nucleus map + CyclinB1*@Nucleus map
  5. CDK1|​Y14/15_pho:​CyclinB1*@Nucleus map → map CDK1|​Y14/15_pho|​T161_pho:​CyclinB1*@Nucleus map
  6. CDK1:​CyclinB1*@Nucleus map + GADD45A@Nucleus map → map CDK1:​CyclinB1*:​GADD45A@Nucleus map
  7. CyclinA1*@Nucleus map + CDK1@Nucleus map → map CDK1:​CyclinA1*@Nucleus map
  8. CDK1:​CyclinA1*@Nucleus map → map CDK1|​Y14/15_pho:​CyclinA1*@Nucleus map
  9. CDK1|​Y14/15_pho:​CyclinA1*@Nucleus map → map (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map
  10. (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map → map (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map
  11. (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map → map (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map
  12. CDK1|​T161_pho:​CyclinB1*@Nucleus map → map CDK1|​T161_pho|​pho:​CyclinB1*@Nucleus map
  13. CDK1|​Y14/15_pho|​T161_pho:​CyclinB1*@Nucleus map → map CDK1|​Y14/15_pho:​CyclinB1*@Nucleus map
  14. CDK1|​T161_pho:​CyclinB1*@Nucleus map + 14-3-3*@Nucleus map → map CDK1|​T161_pho:​CyclinB1*@Nucleus map
  15. CDK1@Cytosol map → map CDK1|​Tyr15_pho|​Thr14_pho@Cytosol map
  16. CDK1|​Tyr15_pho|​Thr14_pho@Cytosol map → map G2/M phase transition@Cytosol map
As Catalyser:
  1. S phase@Nucleus map → map G2 phase@Nucleus map
  2. G2 phase@Nucleus map → map M phase@Nucleus map
  3. TP53BP1@Nucleus map → map TP53BP1|​pho@Nucleus map
  4. E2F1:​RB1@Nucleus map → map E2F1:​RB1|​pho@Nucleus map
  5. WEE1|​CHEK1site_pho@Nucleus map → map WEE1|​pho@Nucleus map
  6. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*|​pho@Nucleus map
  7. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20|​pho:​CyclinA1*@Nucleus map
  8. CDC25A@Nucleus map → map CDC25A|​S18_pho|​S116_pho|​active@Nucleus map
  9. CDC25B@Nucleus map → map CDC25B|​S353_pho|​active@Nucleus map
  10. CDC25C@Nucleus map → map CDC25C|​S191_pho|​S198_pho|​S214_pho|​active@Nucleus map
  11. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  12. PLK1@Nucleus map → map PLK1|​pho|​active@Nucleus map
  13. EMI1*@Nucleus map → map EMI1*|​pho@Nucleus map
  14. Securin*@Nucleus map → map Securin*|​S165_pho@Nucleus map
  15. Caspase9*|​S196_unk|​S144_unk|​Y153_unk@Cytosol map → map Caspase9*|​S196_unk|​T125_pho|​S144_unk|​Y153_unk@Cytosol map
  16. BAD|​unk@Cytosol map → map BAD|​S91_pho|​unk@Cytosol map
  17. BIRC5@Cytosol map → map BIRC5|​T34_pho@Cytosol map
  18. TSC1@Endosome Membrane map → map TSC1|​T417_pho|​S584_pho|​T1047_pho@Endosome Membrane map
  19. TERF1|​hm2@Nucleus map → map TERF1|​T344_pho|​hm2@Nucleus map