Complex ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*
Complex composition:
- ORC5*
- ORC4*
- ORC6*
- ORC2*
- ORC1*
- ORC3*
ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@Nucleus
Identifiers
NAME:ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ S_CC_PHASE
References
ce_re355( Cell Cycle DNA Repair
):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221
Modifications:
Participates in complexes:
In compartment: Nucleus
- ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@Nucleus
Participates in reactions:
As Reactant or Product:- ORC4*@Nucleus
+ ORC5*@Nucleus
+ ORC6*@Nucleus
+ ORC3*@Nucleus
+ ORC2*@Nucleus
+ ORC1*@Nucleus
→
ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@Nucleus
- ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@Nucleus
+ MCM2:MCM3:MCM4:MCM5:MCM6:MCM7@Nucleus
+ CDT1@Nucleus
+ CDC6@Nucleus
+ CDC45@Nucleus
+ POLA*@Nucleus
+ PRIM*@Nucleus
+ RPA1@Nucleus
+ RPA2@Nucleus
+ RPA3@Nucleus
→
CDC45:CDC6:CDT1:MCM2:MCM3:MCM4:MCM5:MCM6:MCM7:ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*:POLA*:PRIM*@Nucleus
As Catalyser: