Protein RPA1 map

Identifiers
replication protein A1
HUGO:RPA1
replication protein A1, 70kDa
HUGO:RPA1, HGNC:10289, ENTREZ:6117, UNIPROT:P27694

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / S_CC_PHASE  map
 Cell Cycle DNA Repair  map  / HR  map
 Cell Cycle DNA Repair  map  / NER  map
 Cell Cycle DNA Repair  map  / MMR  map

References
PMID:19809470, PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249
For S-phase checkpoint
PMID:15459660, PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221, PMID:18677104

RPA1@Nucleus

References
ce_re355( Cell Cycle DNA Repair  map ):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221

Modifications:
In compartment: Nucleus
  1. RPA1@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. RPA1:​RPA2:​RPA3@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. ce_s2743 + ce_s834 + EXO1@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map + PCNA@Nucleus map + RFC*@Nucleus map → map EXO1:​PCNA:​RFC*:​hMutL*:​hMutS*@Nucleus map
  2. RPA1:​RPA2:​RPA3@Nucleus map + SMARCAL1|​pho@Nucleus map → map ce_s1000
  3. BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@Nucleus map + BRCA2@Nucleus map + FANCJ*@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map + FANCN*@Nucleus map + FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@Nucleus map → map BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​FANCJ*:​FANCN*@Nucleus map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map + TOP3A@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
  5. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  6. RPA1@Nucleus map + RPA2|​pho@Nucleus map + RPA3@Nucleus map → map ce_s3289
  7. ATRIP:​ATR|​pho@Nucleus map + CLSPN|​pho@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map ATRIP:​ATR|​pho:​CLSPN|​pho@Nucleus map
  8. RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map RPA1:​RPA2:​RPA3@Nucleus map
As Catalyser:
  1. gHR_DNA_st2*@Nucleus map → map gHR_DNA_st3*@Nucleus map
  2. gFanconi_DNA_st2*@Nucleus map → map gFanconi_DNA_st3*@Nucleus map
  3. TOPBP1@Nucleus map + ATRIP:​ATR|​pho@Nucleus map + CLSPN|​pho@Nucleus map + RAD17|​pho@Nucleus map → map ATRIP:​ATR|​pho:​CLSPN|​pho:​RAD17|​pho:​TOPBP1@Nucleus map
  4. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  5. rRNA primer@Nucleus map → map AMP@Nucleus map + UMP@Nucleus map + CMP@Nucleus map + GMP@Nucleus map