Protein RPA2 map

Identifiers
replication protein A2
HUGO:RPA2
replication protein A2, 32kDa
HUGO:RPA2, HGNC:10290, ENTREZ:6118, UNIPROT:P15927

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / S_CC_PHASE  map
 Cell Cycle DNA Repair  map  / HR  map
 Cell Cycle DNA Repair  map  / NER  map
 Cell Cycle DNA Repair  map  / MMR  map

References
PMID:19809470, PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249
For S-phase checkpoint
PMID:15459660,PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221, PMID:18677104

RPA2|​pho@Nucleus

References
ce_re43:( Cell Cycle DNA Repair  map ) PMID:16731533

RPA2@Nucleus

References
ce_re355( Cell Cycle DNA Repair  map ):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221

Modifications:
In compartment: Nucleus
  1. RPA2@Nucleus map
  2. RPA2|​pho@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. POLD*:​RPA2|​pho@Nucleus map
  2. RAD52:​RPA2|​pho@Nucleus map
  3. RPA1:​RPA2:​RPA3@Nucleus map
  4. CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA2|​pho:​XRCC1|​pho@Nucleus map
  5. CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map
  6. CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. ce_s2743 + ce_s834 + EXO1@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map + PCNA@Nucleus map + RFC*@Nucleus map → map EXO1:​PCNA:​RFC*:​hMutL*:​hMutS*@Nucleus map
  2. RPA1:​RPA2:​RPA3@Nucleus map + SMARCAL1|​pho@Nucleus map → map ce_s1000
  3. CDK7:​CyclinH*:​MNAT1:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XPB*:​XPD*@Nucleus map + ce_s3289 + XAB2:​XPA|​S196_pho@Nucleus map → map CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map
  4. CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map + ERCC1@Nucleus map + XPF*@Nucleus map + XPG*@Nucleus map → map CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@Nucleus map
  5. BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@Nucleus map + BRCA2@Nucleus map + FANCJ*@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map + FANCN*@Nucleus map + FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@Nucleus map → map BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​FANCJ*:​FANCN*@Nucleus map
  6. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map + TOP3A@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
  7. POLE*@Nucleus map + POLD*@Nucleus map + RFC*@Nucleus map + PCNA@Nucleus map + CHTF18@Nucleus map + POLK@Nucleus map + XRCC1|​pho@Nucleus map + ce_s3289 → map CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA2|​pho:​XRCC1|​pho@Nucleus map
  8. RAD52@Nucleus map + ce_s3289 → map RAD52:​RPA2|​pho@Nucleus map
  9. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  10. RPA2@Nucleus map → map RPA2|​pho@Nucleus map
  11. RPA1@Nucleus map + RPA2|​pho@Nucleus map + RPA3@Nucleus map → map ce_s3289
  12. POLD*@Nucleus map + ce_s3289 → map POLD*:​RPA2|​pho@Nucleus map
  13. ATRIP:​ATR|​pho@Nucleus map + CLSPN|​pho@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map ATRIP:​ATR|​pho:​CLSPN|​pho@Nucleus map
  14. RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map RPA1:​RPA2:​RPA3@Nucleus map
As Catalyser:
  1. gGG-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  2. gHR_DNA_st2*@Nucleus map → map gHR_DNA_st3*@Nucleus map
  3. gTC-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  4. gFanconi_DNA_st2*@Nucleus map → map gFanconi_DNA_st3*@Nucleus map
  5. gFanconi_DNA_st5*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map
  6. gSSA_DNA_st2*@Nucleus map → map gSSA_DNA_st3*@Nucleus map
  7. gTC-NER_GG-NER_DNA_st3*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map + Modified 24-32 nucleotides fragment@Nucleus map
  8. gTC-NER_GG-NER_DNA_st4*@Nucleus map + dNTPs@Nucleus map → map gTC-NER_GG-NER_DNA_st5*@Nucleus map
  9. gMMR_DNA_st3*@Nucleus map → map gMMR_DNA_st4*@Nucleus map
  10. TOPBP1@Nucleus map + ATRIP:​ATR|​pho@Nucleus map + CLSPN|​pho@Nucleus map + RAD17|​pho@Nucleus map → map ATRIP:​ATR|​pho:​CLSPN|​pho:​RAD17|​pho:​TOPBP1@Nucleus map
  11. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  12. rRNA primer@Nucleus map → map AMP@Nucleus map + UMP@Nucleus map + CMP@Nucleus map + GMP@Nucleus map