Complex APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*
Complex composition:
- E-Cadherin*
- APC2*
- APC1*
- APC3*
- APC4*
- APC5*
- APC6*
- APC7*
- APC8*
- APC12*
- APC11*
- APC10*
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
Identifiers
NAME:APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ M_CC_PHASE
References
ce_re394( Cell Cycle DNA Repair
):
APC complex/CDH1(de-phosphorylated)-induce M phase exit:
PMID:11598127
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*|pho@Nucleus
Identifiers
NAME:APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ M_CC_PHASE
References
ce_re216( Cell Cycle DNA Repair
):
By CDC20/APC complex:
M to G1 transition
By Mitotic checkpoint complex:
Spindle checkpoint
PARP3 activated spindle checkpoint
PMID:21270334
Tankyrase activated spindle checkpoint
PMID:23197039
Modifications:
Participates in complexes:
In compartment: Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*|pho@Nucleus
Participates in reactions:
As Reactant or Product:- E-Cadherin*@Nucleus
+ APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*@Nucleus
→
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
→
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*|pho@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*|pho@Nucleus
→
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
→
E-Cadherin*@Nucleus
+ APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:E-Cadherin*@Nucleus
→
M phase exit@Nucleus
As Catalyser:- M phase@Nucleus
→
G1 phase@Nucleus
- CyclinA1*@Nucleus
→
degraded
- CyclinB1*@Nucleus
→
degraded
- CDC25A@Nucleus
→
degraded