Protein WEE1 map

Identifiers
WEE1 homolog (S. pombe)
HUGO:WEE1, HGNC:12761, ENTREZ:7465, UNIPROT:P30291

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / G1_CC_PHASE  map
 Cell Cycle DNA Repair  map  / S_CC_PHASE  map
 Cell Cycle DNA Repair  map  / G2_CC_PHASE  map

References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

WEE1|​CHEK1site_pho@Nucleus

References
ce_re603( Cell Cycle DNA Repair  map ):
In response to DNA damage, CHEK1 phosphorylates and activates WEE1, blocks cell cycle and allows DNA repair
PMID:23897299, PMID:23508805
ce_re273:( Cell Cycle DNA Repair  map ) Wee1 phosphorylation of CDC2 keeps the complex inactive

WEE1@Nucleus

References
ce_re603( Cell Cycle DNA Repair  map ):
In response to DNA damage, CHEK1 phosphorylates and activates WEE1, blocks cell cycle and allows DNA repair
PMID:23897299, PMID:23508805

Modifications:
In compartment: Nucleus
  1. WEE1@Nucleus map
  2. WEE1|​pho@Nucleus map
  3. WEE1|​CHEK1site_pho@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. WEE1|​CHEK1site_pho@Nucleus map → map WEE1|​pho@Nucleus map
    2. WEE1|​pho@Nucleus map → map degraded
    3. WEE1@Nucleus map → map WEE1|​CHEK1site_pho@Nucleus map
    As Catalyser:
    1. CDK1:​CyclinB1*@Nucleus map → map CDK1|​Y14/15_pho:​CyclinB1*@Nucleus map
    2. ce_s3119 → map CDK2|​Y14/15_pho:​CyclinE*@Nucleus map
    3. CDK4_6*:​CyclinD*@Nucleus map → map CDK4_6*|​Y14_pho:​CyclinD*@Nucleus map
    4. ce_s3123 → map CDK2|​Y14/15_pho:​CyclinA1*@Nucleus map
    5. CDK1:​CyclinA1*@Nucleus map → map CDK1|​Y14/15_pho:​CyclinA1*@Nucleus map