Protein CDC25A map

Identifiers
cell division cycle 25 homolog A (S. pombe)
HUGO:CDC25A, HGNC:1725, ENTREZ:993, UNIPROT:P30304

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / G1_CC_PHASE  map
 Cell Cycle DNA Repair  map  / S_CC_PHASE  map

References
PMID:1075565, PMID:18073536, PMID:18786381, PMID:17568790, PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

CDC25A|​S76_pho|​S178_pho|​S124_pho|​S279_pho|​S293_pho@Nucleus

References
ce_re65( Cell Cycle DNA Repair  map ):
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790

CDC25A@Nucleus

References
ce_re65( Cell Cycle DNA Repair  map ):
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790

Modifications:
In compartment: Nucleus
  1. CDC25A@Nucleus map
  2. CDC25A|​S18_pho|​S116_pho|​active@Nucleus map
  3. CDC25A|​S76_pho|​S178_pho|​S124_pho|​S279_pho|​S293_pho@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CDC25A|​S76_pho|​S178_pho|​S124_pho|​S279_pho|​S293_pho@Nucleus map → map CDC25A@Nucleus map
    2. CDC25A@Nucleus map → map CDC25A|​S18_pho|​S116_pho|​active@Nucleus map
    3. CDC25A@Nucleus map → map degraded
    4. rCDC25A@Nucleus map → map CDC25A@Nucleus map
    5. CDC25A@Nucleus map → map CDC25A|​S76_pho|​S178_pho|​S124_pho|​S279_pho|​S293_pho@Nucleus map
    As Catalyser:
    1. CDK4_6*|​T172_pho|​Y14_pho:​CyclinD*@Nucleus map → map (CDK4_6*|​T172_pho:​CyclinD*)|​active@Nucleus map
    2. CDK2|​T160_pho|​Y14/15_pho:​CyclinE*@Nucleus map → map (CDK2|​T160_pho:​CyclinE*)|​active@Nucleus map
    3. CDK2|​T160_pho|​Y14/15_pho:​CyclinA1*@Nucleus map → map (CDK2|​T160_pho:​CyclinA1*)|​active@Nucleus map
    4. (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map → map (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@Nucleus map