Protein CDC25C map

Identifiers
cell division cycle 25 homolog C (S. pombe)
HUGO:CDC25C, HGNC:1727, ENTREZ:995, UNIPROT:P30307

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / G2_CC_PHASE  map

References
PMID:1075565, PMID:18073536, PMID:18786381, PMID:17568790, PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

CDC25C@Nucleus

References
ce_re63:( Cell Cycle DNA Repair  map ) kegg cell cycle
ce_re313( Cell Cycle DNA Repair  map ):
Activation by PLK phosphorylation at S191, S198
Activation by CDC2 phosphorylation at S214
PMID:17596790
ce_re316( Cell Cycle DNA Repair  map ):
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790

CDC25C|​S191_pho|​S198_pho|​S214_pho|​active@Nucleus

References
ce_re313( Cell Cycle DNA Repair  map ):
Activation by PLK phosphorylation at S191, S198
Activation by CDC2 phosphorylation at S214
PMID:17596790

CDC25C|​S216_pho@Nucleus

References
ce_re316( Cell Cycle DNA Repair  map ):
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790

Modifications:
In compartment: Nucleus
  1. CDC25C@Nucleus map
  2. CDC25C|​S216_pho@Nucleus map
  3. CDC25C|​S191_pho|​S198_pho|​S214_pho|​active@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CDC25C@Nucleus map → map CDC25C|​S191_pho|​S198_pho|​S214_pho|​active@Nucleus map
    2. CDC25C@Nucleus map → map CDC25C|​S216_pho@Nucleus map
    3. 14-3-3*@Nucleus map + CDC25C@Nucleus map → map ce_s2526
    4. CDC25C|​S216_pho@Nucleus map → map CDC25C@Nucleus map
    As Catalyser:
    1. CDK1|​Y14/15_pho|​T161_pho:​CyclinB1*@Nucleus map → map CDK1|​T161_pho:​CyclinB1*@Nucleus map