Protein TOPBP1
Identifiers
topoisomerase (DNA) II binding protein 1
HUGO:TOPBP1, HGNC:17008, ENTREZ:11073, UNIPROT:Q92547
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ G2_M_CHECKPOINT
References
PMID:17303408, PMID:16530042
Modifications:
In compartment: Nucleus
- TOPBP1@Nucleus
Participates in complexes:
In compartment: Nucleus
- ATRIP:ATR|pho:CLSPN|pho:RAD17|pho:TOPBP1@Nucleus
Participates in reactions:
As Reactant or Product:- TOPBP1@Nucleus
+ ATRIP:ATR|pho@Nucleus
+ CLSPN|pho@Nucleus
+ RAD17|pho@Nucleus
→
ATRIP:ATR|pho:CLSPN|pho:RAD17|pho:TOPBP1@Nucleus
As Catalyser:- CHEK1@Nucleus
→
CHEK1|pho|active@Nucleus