Simple molecule AMP
AMP@default
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ INHIBITING_CHECKPOINTS
AMP@Nucleus
Identifiers
adenosine 5'-monophosphate
CHEBI:16027
AMP@Cytosol
Identifiers
CHEBI:16027 KEGGCOMPOUND:C00020 CAS:61-19-8
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ FERROPTOSIS
References
PMID:27048822
PMID:26653790
PMID:26794443
ACSF2 and CS are required for mitochondrial fatty-acid metabolism in ferroptosis.
Knockdown of ACSF2 and CS inhibits erastin-induced ferroptosis
AMP@Mitochondrial Matrix
Identifiers
CHEBI:16027 KEGGCOMPOUND:C00020 CAS:61-19-8
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ FERROPTOSIS
Regulated Cell Death
/ FATTY_ACID_BIOSYNTHESIS
Regulated Cell Death
/ MITOCHONDRIAL_METABOLISM
References
PMID:27048822
PMID:26653790
PMID:26794443
ACSF2 and CS are required for mitochondrial fatty-acid metabolism in ferroptosis.
Knockdown of ACSF2 and CS inhibits erastin-induced ferroptosis
AMP@Mitochondrial inner membrane
Identifiers
CHEBI:16027 KEGGCOMPOUND:C00020 CAS:61-19-8
Modifications:
In compartment: Cytosol
- AMP@Cytosol
In compartment: Mitochondrial Matrix
- AMP@Mitochondrial Matrix
In compartment: Mitochondrial inner membrane
- AMP@Mitochondrial inner membrane
In compartment: Nucleus
- AMP@Nucleus
In compartment: default
- AMP@default
Participates in complexes:
In compartment: Cytosol
- AMP:PKA_R*:PRKAA*:PRKAG*@Cytosol
- AMP:PKA_R*:PRKAA*|T172_pho:PRKAG*@Cytosol
Participates in reactions:
As Reactant or Product:- ATP@default
→
AMP@default
- AMP@default
→
Adenosine@default
- acetate@Mitochondrial Matrix
+ ATP@Mitochondrial Matrix
+ coenzyme A@Mitochondrial Matrix
→
acetyl-CoA@Mitochondrial Matrix
+ AMP@Mitochondrial Matrix
- acetate@Cytosol
+ ATP@Cytosol
+ coenzyme A@Cytosol
→
acetyl-CoA@Cytosol
+ AMP@Cytosol
- ADP@Cytosol
→
ATP@Cytosol
+ AMP@Mitochondrial inner membrane
- ADP-ribose@Nucleus
+ H20@Nucleus
→
AMP@Nucleus
+ Ribose-1-P@Nucleus
- AMP@Nucleus
→
High AMP level@Nucleus
- L-cysteine@Cytosol
+ tRNACys@Cytosol
+ ATP@Cytosol
→
Cys-tRNA(Cys)@Cytosol
+ diphosphate@Cytosol
+ AMP@Cytosol
- AMP:PKA_R*:PRKAA*:PRKAG*@Cytosol
→
AMP:PKA_R*:PRKAA*|T172_pho:PRKAG*@Cytosol
- ATP:PKA_R*:PRKAA*:PRKAG*@Cytosol
+ AMP@Cytosol
→
AMP:PKA_R*:PRKAA*:PRKAG*@Cytosol
+ ATP@Cytosol
- AMP:PKA_R*:PRKAA*:PRKAG*@Cytosol
→
AMP:PKA_R*:PRKAA*|T172_pho:PRKAG*@Cytosol
- ribose-5P@Cytosol
+ ATP@Cytosol
→
PRPP@Cytosol
+ AMP@Cytosol
- rRNA primer@Nucleus
→
AMP@Nucleus
+ UMP@Nucleus
+ CMP@Nucleus
+ GMP@Nucleus
As Catalyser:- ACACA@Cytosol
→
ACACA|S79_pho@Cytosol
- JNK1*@Cytosol
→
JNK1*|pho|active@Cytosol
- ULK*@Cytosol
→
ULK*|Ser 317_pho|Ser 777_pho@Cytosol
- fructose-1,6P2@Cytosol
→
fructose-6P@Cytosol
- PFKFB3@Cytosol
→
PFKFB3|pho@Cytosol
- PFKFB2@Cytosol
→
PFKFB2|pho@Cytosol
- TSC1:TSC2|M1_unk@Cytosol
→
TSC1:TSC2|S1345_pho|M1_unk@Cytosol
- RPTOR@Cytosol
→
RPTOR|S722_pho|S792_pho@Cytosol
- Caspase3*@Cytosol
→
cleaved~Caspase3*@Cytosol