Protein TOP3A map

Identifiers
topoisomerase (DNA) III alpha
HUGO:TOP3A, HGNC:11992, ENTREZ:7156, UNIPROT:Q13472

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / HR  map
 Cell Cycle DNA Repair  map  / FANCONI  map

References
For HR pathway
PMID:19772495, PMID:16697054, PMID:19847258
For Fanconi anemia pathway
PMID:19686080, PMID:19622404, PMID:18931676

Modifications:
In compartment: Nucleus
  1. TOP3A@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. BLM:​RMI1:​TOP3A@Nucleus map
  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. TOP3A@Nucleus map + BLM@Nucleus map + RMI1@Nucleus map → map BLM:​RMI1:​TOP3A@Nucleus map
  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map + TOP3A@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
As Catalyser:
  1. gHR_DNA_st1*@Nucleus map → map gHR_DNA_st2*@Nucleus map
  2. gHR_DNA_st5*@Nucleus map → map gHR_DNA_st6*@Nucleus map