Reaction state_transition rc_re53
isocitrate@Mitochondrial Matrix
+
H+@Mitochondrial Matrix
+
NADP_super_+_endsuper_@Mitochondrial Matrix
→
2-oxoglutarate@Mitochondrial Matrix
+
CO_sub_2_endsub_@Mitochondrial Matrix
+
NADPH@Mitochondrial Matrix
Reaction regulators:
Catalysis
IDH2|hm2:Mg2+@Mitochondrial Matrix
+ H+@Mitochondrial Matrix + NADP_super_+_endsuper_@Mitochondrial Matrix → 2-oxoglutarate@Mitochondrial Matrix + CO_sub_2_endsub_@Mitochondrial Matrix + NADPH@Mitochondrial Matrix