Reaction state_transition rc_re833
protoporphyrin IX@Mitochondrial intermembrane space
+ Fe2+@Mitochondrial intermembrane space
→ ferroheme b@Mitochondrial intermembrane space
+ H+@Mitochondrial intermembrane space
Reaction regulators:
- Catalysis
- FECH|hm2|[2FE-2S]@Mitochondrial intermembrane space
References
PMID:10561552
caracterization of human ferrochelatase as a Fe-S homodimer
PMID:16839620
review heme biosynthesis in mammals