Identifiers
CHEBI:16452 KEGGCOMPOUND:C00036 CAS:149-63-3
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / FERROPTOSIS
Regulated Cell Death / FATTY_ACID_BIOSYNTHESIS
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
References
PMID:27048822
PMID:26653790
PMID:26794443
ACSF2 and CS are required for mitochondrial fatty-acid metabolism in ferroptosis.
Knockdown of ACSF2 and CS inhibits erastin-induced ferroptosis
rc_re50( Regulated Cell Death ):
influenceDelete: re to NAD_super_+_endsuper_@mitochondrial matrix
influenceDelete: NAD_super_+_endsuper_@mitochondrial matrix to re
influenceDelete: re to H_super_+_endsuper_@mitochondrial matrix
Identifiers
CHEBI:16452 KEGGCOMPOUND:C00036 CAS:149-63-3
References
charge:2-