Identifiers
CHEBI:29052 KEGGCOMPOUND:C00118 CAS:591-57-1
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / PARTHANATOS
References
rc_re253:( Regulated Cell Death ) Dihydroxyacetone phosphate lies in the glycolysis metabolic pathway, and is one of the two products of breakdown of fructose 1,6-bisphosphate, along with glyceraldehyde 3-phosphate.
rc_re254:( Regulated Cell Death ) PMID:8061610
rc_re1182:( Regulated Cell Death ) source UNIPROT and KEGGPATHWAY
rc_re1465( Regulated Cell Death ):
PMID:20103683
in head and neck squamous cell carcinoma cells, enhanced TKTL1 expression and promoter hypomethylation
TKTL1 overexpression associated with increased growth
increase in F6P and glyceraldehyde-3P
increase in glycolysis in a HIF1 dependent manner
they propose that TKTL1 promotes F6P and glyceraldehyde 3P, displayed here as the reverse reaction