Protein FANCI
Identifiers
Fanconi anemia, complementation group I
HUGO:FANCI, HGNC:25568, ENTREZ:55215, UNIPROT:Q9NVI1
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair
/ FANCONI
References
PMID:19686080, PMID:19622404, PMID:18931676, PMID:22101340
FANCI|pho@Nucleus
References
ce_re160( Cell Cycle DNA Repair
):
PMID:18931676
PMID:19686080
Link between cell cycle and activation of Fanconi pathway
FANCI@Nucleus
References
ce_re160( Cell Cycle DNA Repair
):
PMID:18931676
PMID:19686080
Link between cell cycle and activation of Fanconi pathway
Modifications:
In compartment: Nucleus
- FANCI@Nucleus
- FANCI|pho@Nucleus
- FANCI|K523_ubi|pho@Nucleus
Participates in complexes:
In compartment: Nucleus
- FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@Nucleus
- FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:POLN@Nucleus
- BRCA1:BRCA2:FANCD2|pho:FANCI|pho:FANCJ*:FANCN*@Nucleus
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:FANCJ*:FANCN*@Nucleus
- BRCA1:BRCA2:FANCD2|pho:FANCI|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@Nucleus
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@Nucleus
Participates in reactions:
As Reactant or Product:- FANCI|pho@Nucleus
→
FANCI|K523_ubi|pho@Nucleus
- FANCI@Nucleus
→
FANCI|pho@Nucleus
- FANCD2|K561_ubi|pho@Nucleus
+ FANCI|K523_ubi|pho@Nucleus
→
FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@Nucleus
- FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@Nucleus
+ BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@Nucleus
+ BRCA2@Nucleus
+ NBS1*|S343_pho@Nucleus
+ RAD51@Nucleus
+ PCNA@Nucleus
+ H2AFX|S139_pho|ubi@Nucleus
+ TIP60*@Nucleus
→
BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@Nucleus
- BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@Nucleus
+ BRCA2@Nucleus
+ FANCJ*@Nucleus
+ RPA1:RPA2:RPA3@Nucleus
+ FANCN*@Nucleus
+ FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@Nucleus
→
BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:FANCJ*:FANCN*@Nucleus
- FANCI|K523_ubi|pho@Nucleus
→
FANCI|pho@Nucleus
- FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@Nucleus
+ POLN@Nucleus
→
FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:POLN@Nucleus
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@Nucleus
→
BRCA1:BRCA2:FANCD2|pho:FANCI|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@Nucleus
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:FANCJ*:FANCN*@Nucleus
→
BRCA1:BRCA2:FANCD2|pho:FANCI|pho:FANCJ*:FANCN*@Nucleus
As Catalyser:- G2 phase@Nucleus
→
M phase@Nucleus
- gHR_DNA_st2*@Nucleus
→
gHR_DNA_st3*@Nucleus
- gHR_DNA_st3*@Nucleus
→
gHR_DNA_st4*@Nucleus
- gFanconi_DNA_st4*@Nucleus
→
gFanconi_DNA_st5*@Nucleus
- gFanconi_DNA_st4*@Nucleus
→
gHR_DNA_st2*@Nucleus