Gene Fanconi_DNA_st4* map

Identifiers
Fanconi:DNA:st4
Reversed-fork structured DNA with unhooked and insices inter chromasomal crosslinks (ICL) region
Node_Type:Generic

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / FANCONI  map

gFanconi_DNA_st4*@Nucleus

References
ce_re162( Cell Cycle DNA Repair  map ):
Link between HR, NER to Fanconi anemia pathway.
PMID:19686080
For ERCC1/XPF:
PMID:10882712, PMID:19805513
For MUS81/Eme1:
PMID:17036055:G
FANCA modulates XPF function:
MRN complex, FANCD2 and SNM1B are modulators of the DNA to release stalled fork:
PMD:19622404
ce_re163( Cell Cycle DNA Repair  map ):
POLH activates D-loop extention
PoLN:HEL308* participate in HR and Fanconi. PolN:FANCD2:FANCI complex activate HR:
PMID:16337602
Presence of FA core complex is essential for thePolZ/Rev1 activity:
PMID:18448394
PoLQ/HEL308 in Fancon:
PMID:18472307
ce_re165( Cell Cycle DNA Repair  map ):
Link between Fanconi pathway and HR.
Fanconi pathway is a coordination of NER, TLS and HR
PMID:19686080:G
POLH activates D-loop extension. PoLN:HEL308* participate in HR and Fanconi. PolN:FANCD2:FANCI complex activate HR:
For role of SMARCAL1/RPA in stalled replication fork repair and in the homologous recombination:
PMID:19841479, PMID:19793861, PMID:19793862

Modifications:
In compartment: Nucleus
  1. gFanconi_DNA_st4*@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gFanconi_DNA_st3*@Nucleus map → map gFanconi_DNA_st4*@Nucleus map
    2. gFanconi_DNA_st4*@Nucleus map → map gFanconi_DNA_st5*@Nucleus map
    3. gFanconi_DNA_st4*@Nucleus map → map gHR_DNA_st2*@Nucleus map
    As Catalyser: