Protein POLN map

Identifiers
polymerase (DNA directed) nu
HUGO:POLN, HGNC:18870, ENTREZ:353497, UNIPROT:Q7Z5Q5

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / A_NHEJ  map
 Cell Cycle DNA Repair  map  / HR  map
 Cell Cycle DNA Repair  map  / FANCONI  map

References
For HR
PMID:19772495, PMID:16697054, PMID:19847258
For A_NHEJ
PMID:18584027, PMID:17965729, PMID:20064462, PMID:18809224
PMID:18809224, PMID:18584027, PMID:19772495, PMID:18087292
Complex PolN:HEL308 participates in HR and in Fanconi pathways
PMID:19995904

POLN@Nucleus

References
ce_re212( Cell Cycle DNA Repair  map ):
PolN is degraded after S-phase by G2/M cell cycle checkpoint
PMID:19995904

Modifications:
In compartment: Nucleus
  1. POLN@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. HEL308*:​POLN@Nucleus map
  2. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. POLN@Nucleus map + HEL308*@Nucleus map → map HEL308*:​POLN@Nucleus map
  2. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@Nucleus map + POLN@Nucleus map → map FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@Nucleus map
  3. POLN@Nucleus map → map degraded
As Catalyser:
  1. gA_NHEJ_DNA_st4*@Nucleus map → map gA_NHEJ_DNA_st5*@Nucleus map
  2. gHR_DNA_st3*@Nucleus map → map gHR_DNA_st4*@Nucleus map
  3. gFanconi_DNA_st4*@Nucleus map → map gFanconi_DNA_st5*@Nucleus map
  4. gFanconi_DNA_st4*@Nucleus map → map gHR_DNA_st2*@Nucleus map