Reaction heterodimer_association ce_re166 map

FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@Nucleus map + BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@Nucleus map + BRCA2@Nucleus map + NBS1*|​S343_pho@Nucleus map + RAD51@Nucleus map + PCNA@Nucleus map + H2AFX|​S139_pho|​ubi@Nucleus map + TIP60*@Nucleus map → BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​H2AFX|​S139_pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@Nucleus map

No reaction regulators

References
Fanconi recognition complex as FA core complex recruits NER, HR, TLS proteins that collectively repair the ICL. If Fanconi proteins participating in the recognition are dysactivated, there is no any other mechanism to recognize ILSs, therefore, even if NER, HR and TLS are correct, they will not perform the repair without core Fanconi proteins.
PMID:19686080