Reaction state_transition rc_re352 map

TSC1:​TSC2|​M1_unk@Cytosol map → TSC1:​TSC2|​S1345_pho|​M1_unk@Cytosol map

Reaction regulators:
Boolean_logic_gate_and
  1. SESN2@Cytosol map and AMP:​PKA_R*:​PRKAA*|​T172_pho:​PRKAG*@Cytosol map
Catalysis
  1. SESN2@Cytosol map
  2. AMP:​PKA_R*:​PRKAA*|​T172_pho:​PRKAG*@Cytosol map


References
PMID:14651849
PMID:19339977
review
PMID:18692468
SESN2 promotes TSC2 phosphorylation, and interacts with both AMPK and TSC2.