Reaction state_transition rc_re96 map

Caspase3*@Cytosol map → cleaved~Caspase3*@Cytosol map

Reaction regulators:
Catalysis
  1. AMP:​PKA_R*:​PRKAA*|​T172_pho:​PRKAG*@Cytosol map
  2. cleaved~Caspase9*@Cytosol map
  3. cleaved~Caspase8*@Cytosol map
  4. cleaved Caspase 10*@Cytosol map


References
PMID:10508159
CASP3 cleavage by cathepsin D as data not shown
PMID:12208500
sustained activation of AMPK induces Caspase 3 cleavage and so lead to apoptosis triggering