Protein PFKFB3 map

Identifiers
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
HUGO:PFKFB3 HGNC:8874 ENTREZ:5209 UNIPROT:Q16875

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 RECON2  map

PFKFB3@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re271( Regulated Cell Death  map ):
PMID:16115917
phosphorylation at S461 (isoform PFKFB3-ACG) in different tumor cells
in COS-7, expression of a phosphomimetic mutant enhances glycolysis
PMID:17712357
by AMPK review
rc_re1168:( Regulated Cell Death  map ) reactionType:is.a

PFKFB3|​pho@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re271( Regulated Cell Death  map ):
PMID:16115917
phosphorylation at S461 (isoform PFKFB3-ACG) in different tumor cells
in COS-7, expression of a phosphomimetic mutant enhances glycolysis
PMID:17712357
by AMPK review
rc_re1167:( Regulated Cell Death  map ) reactionType:is.a

PFKFB3|​unk@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re1167:( Regulated Cell Death  map ) reactionType:is.a
rc_re1169( Regulated Cell Death  map ):
PMID:19448625
in rat cortical neuron primary culture

PFKFB3|​unk|​ubi@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re1169( Regulated Cell Death  map ):
PMID:19448625
in rat cortical neuron primary culture

Modifications:
In compartment: Cytosol
  1. PFKFB3@Cytosol map
  2. PFKFB3|​pho@Cytosol map
  3. PFKFB3|​unk@Cytosol map
  4. PFKFB3|​unk|​ubi@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. PFKFB3|​pho@Cytosol map → map PFKFB3|​unk@Cytosol map
    2. PFKFB3@Cytosol map → map PFKFB3|​unk@Cytosol map
    3. PFKFB3|​unk@Cytosol map → map PFKFB3|​unk|​ubi@Cytosol map
    4. PFKFB3|​unk|​ubi@Cytosol map → map degraded
    5. rPFKFB3@Nucleus map → map PFKFB3@Cytosol map
    6. PFKFB3|​pho@Cytosol map → map PFKFB*|​hm2@Cytosol map
    7. PFKFB3@Cytosol map → map PFKFB3|​pho@Cytosol map
    As Catalyser: