Protein FAAP24* map

Identifiers
chromosome 19 open reading frame 40, "Fanconi anemia-associated protein, 24 kDa"
HUGO:C19orf40, HGNC:28467, ENTREZ:91442, UNIPROT:Q9BTP7

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / FANCONI  map
 Cell Cycle DNA Repair  map  / TLS  map

References
PMID:19686080, PMID:19622404, PMID:18931676
FANCM/FAAP24 is a sensor of ICL and recruiter of Fanconi core complex
PMID:19622404
HCLK2*/FANCM/FAAP24/active ATR complex inhibit S-phase
PMID:19282663, PMID:19622404
FA core complex regulates REV1 and activated TLS
PMID:22266823

FAAP24*@Nucleus

References
ce_re199( Cell Cycle DNA Repair  map ):
HCLK2*/FANCM/FAAP24/active ATR complex inhibit S-phase:
PMID:19282663, PMID:19622404, PMID:18995830

Modifications:
In compartment: Nucleus
  1. FAAP24*@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. FAAP24*:​FANCM@Nucleus map
  2. ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@Nucleus map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. FAAP24*@Nucleus map + FANCM@Nucleus map → map FAAP24*:​FANCM@Nucleus map
  2. FANCA|​pho:​FANCG|​S7_pho@Nucleus map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@Nucleus map + FAAP24*:​FANCM@Nucleus map + FAAP100*:​FANCB:​FANCL@Nucleus map + BLM@Nucleus map + HES1@Nucleus map + FAAP20*@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map
  3. HCLK2*@Nucleus map + FAAP24*@Nucleus map + FANCM@Nucleus map + ATR|​pho|​active@Nucleus map → map ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@Nucleus map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map + TOP3A@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
As Catalyser:
  1. S phase@Nucleus map → map G2 phase@Nucleus map
  2. G2 phase@Nucleus map → map M phase@Nucleus map
  3. gFanconi_DNA_st1*@Nucleus map → map gFanconi_DNA_st2*@Nucleus map
  4. gFanconi_DNA_st2*@Nucleus map → map gFanconi_DNA_st3*@Nucleus map
  5. FANCD2|​pho@Nucleus map → map FANCD2|​K561_ubi|​pho@Nucleus map
  6. FANCI|​pho@Nucleus map → map FANCI|​K523_ubi|​pho@Nucleus map
  7. gFanconi_DNA_st4*@Nucleus map → map gFanconi_DNA_st5*@Nucleus map
  8. FANCD2@Nucleus map → map FANCD2|​pho@Nucleus map
  9. FANCD2|​K561_ubi|​pho@Nucleus map + MRE11*:​NBS1*|​S343_pho:​RAD50@Nucleus map + ATR|​pho|​active@Nucleus map → map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@Nucleus map
  10. gTLS_DNA_st1*@Nucleus map → map gTLS_DNA_st2*@Nucleus map