Protein FAAP20*
Identifiers
chromosome 1 open reading frame 86
HUGO:C1orf86, HGNC:26428, ENTREZ:199990, UNIPROT:Q6NZ36
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair
/ FANCONI
Cell Cycle DNA Repair
/ TLS
References
FA core complex regulates REV1 and activated TLS
PMID:22266823
Modifications:
In compartment: Nucleus
- FAAP20*@Nucleus
Participates in complexes:
In compartment: Nucleus
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@Nucleus
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1:TOP3A@Nucleus
Participates in reactions:
As Reactant or Product:- FANCA|pho:FANCG|S7_pho@Nucleus
+ FANCC:FANCE|S376_pho|T346_pho:FANCF@Nucleus
+ FAAP24*:FANCM@Nucleus
+ FAAP100*:FANCB:FANCL@Nucleus
+ BLM@Nucleus
+ HES1@Nucleus
+ FAAP20*@Nucleus
→
BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@Nucleus
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@Nucleus
+ TOP3A@Nucleus
+ RPA1:RPA2:RPA3@Nucleus
→
BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1:TOP3A@Nucleus
As Catalyser:- gFanconi_DNA_st2*@Nucleus
→
gFanconi_DNA_st3*@Nucleus
- FANCD2|pho@Nucleus
→
FANCD2|K561_ubi|pho@Nucleus
- FANCI|pho@Nucleus
→
FANCI|K523_ubi|pho@Nucleus
- gFanconi_DNA_st4*@Nucleus
→
gFanconi_DNA_st5*@Nucleus
- FANCD2@Nucleus
→
FANCD2|pho@Nucleus
- FANCD2|K561_ubi|pho@Nucleus
+ MRE11*:NBS1*|S343_pho:RAD50@Nucleus
+ ATR|pho|active@Nucleus
→
ATR|pho:FANCD2|K561_ubi|pho:MRE11*:NBS1*|S343_pho:RAD50@Nucleus
- gTLS_DNA_st1*@Nucleus
→
gTLS_DNA_st2*@Nucleus